BENZNIDAZOLE - ORAL

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BENZNIDAZOLE - ORAL

PHONETIC PRONUNCIATION: (benz-NID-a-zole)

GENERIC NAME(S): benznidazole

Uses

USES: Benznidazole is an antibiotic that is used to treat a certain parasitic infection (Chagas disease). It works by stopping the growth of a certain parasite. This antibiotic treats only Chagas disease. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.


How to use BENZNIDAZOLE - ORAL

HOW TO USE: Read the Instructions for Use if available from your pharmacist before you start taking benznidazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually twice daily (about 12 hours apart). The dosage is based on your weight. If you have trouble swallowing the tablet, you can dissolve it in a cup of water for 1 to 2 minutes. Swirl the cup gently to mix and then drink the mixture right away. Rinse the cup with more water and drink the rinse water to make sure you have taken the whole dose. The amount of water needed to dissolve the tablet and also to rinse your cup depends on your dose. Ask your pharmacist or doctor for specific instructions. For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same times every day. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection. Tell your doctor if your condition lasts or gets worse.

Side Effects

SIDE EFFECTS: Dizziness, headache, abdominal pain, nausea/vomiting, loss of appetite, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: numbness/tingling of arms/legs, easy bruising/bleeding, unusual tiredness. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever that doesn't go away, new or worsening lymph node swelling, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking benznidazole, tell your doctor or pharmacist if you are allergic to it; or to related antibiotics (such as metronidazole, tinidazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain blood disorders (low blood cell counts). Avoid alcoholic beverages and products containing propylene glycol while taking this medication and for at least 3 days after finishing this medicine because severe stomach upset/cramps, nausea, vomiting, headache, and flushing may occur. This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This drug may affect genetic information in cells (genotoxic). Talk to your doctor about the risks and benefits of this medication. Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using benznidazole. Benznidazole may harm an unborn baby. Women of childbearing age should have a pregnancy test before starting this medication. Ask about reliable forms of birth control while using this medication and for 5 days after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. This medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor for more details.

Interactions

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for BENZNIDAZOLE - ORAL

Benznidazole is an antiparasitic medication used to treat Chagas disease, a tropical parasitic infection caused by Trypanosoma cruzi.

Benznidazole works by killing the parasites causing Chagas disease. It is a nitroimidazole compound that interferes with the synthesis of DNA and proteins essential for the survival of the parasite.

Chagas disease is a tropical parasitic infection caused by the parasite Trypanosoma cruzi. It is primarily transmitted through the bite of triatomine bugs, also known as kissing bugs. The disease can cause long-term complications such as heart problems and digestive issues if left untreated.

Benznidazole is generally taken orally, as directed by your healthcare professional. The dosage and duration of treatment depend on several factors, including your age, weight, and the severity of the infection. It is usually taken with meals to minimize stomach upset.

Yes, Benznidazole may cause side effects like nausea, vomiting, loss of appetite, headaches, dizziness, and skin rash. In rare cases, it can cause more serious side effects like liver problems or allergic reactions. It is important to discuss any concerning symptoms with your doctor.

It is generally recommended to avoid consuming alcohol while taking Benznidazole, as it may increase the risk of liver damage.

Benznidazole is not recommended for use during pregnancy, especially during the first trimester, as it may harm the developing fetus. It is also not recommended while breastfeeding, as it can pass into breast milk and potentially harm the infant. Consult your doctor if you are pregnant or breastfeeding.

The length of treatment varies depending on the individual and the severity of the infection. Generally, treatment with Benznidazole can last for several weeks to several months. It is essential to complete the full course of treatment as prescribed, even if symptoms improve.

Benznidazole is primarily used for the treatment of Chagas disease and is not commonly used for prevention. Preventive strategies for Chagas disease mainly focus on vector control, such as avoiding exposure to triatomine bugs and improving housing conditions.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.