BARICITINIB - ORAL

BARICITINIB - ORAL

PHONETIC PRONUNCIATION: (BAR-i-SYE-ti-nib)

COMMON BRAND NAME(S): Olumiant

GENERIC NAME(S): baricitinib

Uses

USES: Baricitinib is used to treat rheumatoid arthritis. It helps decrease pain, tenderness, and swelling in the joints.


How to use BARICITINIB - ORAL

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking baricitinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

SIDE EFFECTS: See also Warning section. People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you have any serious side effects, including: signs of anemia (such as unusual tiredness, pale skin, fast heartbeat), signs of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine), signs of a serious tear in the stomach or intestinal wall (such as severe stomach/abdominal pain that doesn't go away, fever, severe dizziness, fainting, severe nausea/vomiting). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: See also Warning section. Before taking baricitinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood/bone marrow problems (such as anemia), cancer, kidney disease, liver disease (such as hepatitis B or C), past/recent/current infections (such as tuberculosis, herpes zoster, HIV infection), stomach/intestinal problems (such as ulcers, diverticulitis). Baricitinib can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. However, because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for BARICITINIB - ORAL

- Baricitinib is an oral medication that belongs to a class of drugs known as Janus kinase (JAK) inhibitors. It is primarily used to treat rheumatoid arthritis in adults.

- Baricitinib works by suppressing the immune system and reducing inflammation in the body. It inhibits specific enzymes called Janus kinases, which play a role in the immune response and the inflammation process.

- The common side effects of baricitinib may include upper respiratory tract infections, headaches, nausea, diarrhea, and an increased risk of serious infections. It is important to discuss these potential side effects with your healthcare provider.

- Baricitinib is not currently approved for use in children or adolescents. It is only indicated for use in adults with certain conditions.

- Baricitinib is taken orally as a tablet once daily. The recommended starting dosage is usually 2 mg per day, but it may be adjusted based on the patient's response and individual needs.

- It is recommended to avoid using baricitinib during pregnancy unless the potential benefits outweigh the risks. It is also advised to discontinue the medication while breastfeeding, as its safety in breast milk is not known.

- Baricitinib may interact with certain medications, such as strong CYP3A4 inhibitors or inducers, immunosuppressive drugs, and live vaccines. It is important to inform your healthcare provider about all the medications you are taking to avoid potential interactions.

- The onset of action for baricitinib can vary among individuals. Some patients may start experiencing improvements in their symptoms within a few weeks, while others may take longer. It is essential to follow the recommended dosage and treatment duration for optimal results.

- Baricitinib can be used alone or in combination with other disease-modifying antirheumatic drugs (DMARDs) for the treatment of rheumatoid arthritis, as recommended by your healthcare provider.


Warning

WARNING: Baricitinib may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. The most common serious infections include pneumonia, shingles, and urinary tract infections. The risk for infections may be higher if you also take other drugs that suppress the immune system (such as methotrexate, corticosteroids). Tell your doctor right away if you have any signs of infection (such as a sore throat that doesn't go away, fever, chills, cough, painful/frequent urination, non-healing skin sores). You should have a tuberculosis (TB) skin test before and during treatment with this medication. Tell your doctor if you have been near someone with tuberculosis or have lived or traveled in areas where certain fungal infections (such as coccidioidomycosis, histoplasmosis) are common. These areas include the Ohio and Mississippi River valleys and the southwestern United States. Though it is very unlikely to occur, there may be a risk of developing cancer (such as lymphoma, skin cancer) with this medication. Tell your doctor right away if you develop symptoms such as fever that doesn't go away, unusual lumps/growths, unexplained weight loss, night sweats, change in appearance or size of moles, or unusual skin changes. Baricitinib may rarely cause serious blood clots to form in the legs or lungs. Tell your doctor if you have a history of blood clots (such as deep vein thrombosis, pulmonary embolism). Get medical help right away if you develop symptoms of a blood clot, including shortness of breath/rapid breathing, chest pain, or pain/swelling/warmth in the groin/calf.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.