ANTIHEMOPHILIC FACTOR (FACTOR VIII), RECOMBINANT - INJECTION
PHONETIC PRONUNCIATION: (AN-tye-HEE-moe-FIL-ik FAK-tor, ree-KOM-bi-nant)
COMMON BRAND NAME(S): Advate, Adynovate, Kogenate, Obizur, Recombinate
GENERIC NAME(S): antihemophilic factor VIII, human recombinant
Uses
USES: This medication is used to control and prevent bleeding episodes in people with low levels of factor VIII (hemophilia A). It is also used in these patients before surgery to prevent bleeding. People with low factor VIII levels are at risk for bleeding longer after an injury/surgery and for bleeding inside the body (especially into the joints and muscles). This product contains a man-made form of factor VIII, also called antihemophilic factor. This product is used to temporarily replace the missing factor VIII, a protein (clotting factor) that is normally in the blood, so that the blood can clot and the bleeding can stop. This medication should not be used to treat von Willebrand disease.
How to use ANTIHEMOPHILIC FACTOR (FACTOR VIII), RECOMBINANT - INJECTION
HOW TO USE: This medication is given by injection into a vein as directed by your doctor. The medication may need to be given more slowly over a longer time depending on your dose and how you respond to it. After first receiving this medication in a hemophilia treatment center or hospital, some patients may be able to give this medication to themselves at home. If your doctor directs you to give this medication at home, read the Patient Information Leaflet available from your pharmacist before you start using this medication and each time you get a refill. Learn all preparation and usage instructions in the product package. Learn how to store and discard needles and medical supplies safely. If you have any questions, ask your health care professional. If the medication and the solution used to mix it were refrigerated, bring both to room temperature before combining. After adding the solution to the powder, gently swirl the mixture to completely dissolve the powder. Do not shake. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. Use right away according to the product instructions. The dosage is based on your medical condition, weight, blood test results, and response to treatment. Follow your doctor's instructions closely. Tell your doctor if your condition does not improve or if it worsens.
Side Effects
Precautions
Interactions
Overdose
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Faq for ANTIHEMOPHILIC FACTOR (FACTOR VIII), RECOMBINANT - INJECTION
Antihemophilic factor (Factor VIII), recombinant is a medication used to treat and prevent bleeding episodes in patients with hemophilia A, a genetic disorder that impairs the blood's clotting ability. It works by replacing or increasing the levels of Factor VIII in the blood, which is necessary for proper blood clotting.
Common side effects of this medication include headache, fever, chills, nausea, vomiting, rash, itching, injection site reactions, and joint pain.
Antihemophilic factor (Factor VIII), recombinant is given by intravenous (IV) injection into a vein. It is usually administered in a healthcare setting under the supervision of a healthcare professional. Dosage and frequency of administration depend on individual patient needs and the severity of hemophilia A.
Before using this medication, inform your healthcare provider about any allergies, medical conditions, and all other medications you are currently taking. It is important to disclose if you have a history of blood clots or inhibitors to Factor VIII. This medication should not be used during pregnancy unless necessary, as the safety for unborn babies is not well-established.
Yes, this medication can be used in children with hemophilia A, following appropriate dosing guidelines and under the supervision of a healthcare professional. However, the use of antihemophilic factor (Factor VIII), recombinant in infants less than 6 months old should be done with caution due to a higher risk of developing inhibitors.
If you miss a dose, contact your healthcare provider or hemophilia treatment center for instructions. It is important to adhere to the prescribed dosing schedule to maintain adequate Factor VIII levels in the blood.
Drug interactions are not well-documented for this medication. However, it is always important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid any potential interactions.
This medication should be stored in the refrigerator at a temperature between 2-8 degrees Celsius (36-46 degrees Fahrenheit). It should not be frozen. Always check the manufacturer's instructions for specific storage requirements and expiration dates.
In case of an overdose, seek immediate medical attention. Overdosing on antihemophilic factor (Factor VIII), recombinant may potentially increase the risk of blood clot formation.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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By Ali saeed al rwaihi on 08 Apr, 2021