AMIFOSTINE - INJECTION

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AMIFOSTINE - INJECTION

PHONETIC PRONUNCIATION: (A-mi-FOS-teen)

COMMON BRAND NAME(S): Ethyol

GENERIC NAME(S): amifostine crystalline

Uses

USES: Amifostine is used to decrease the risk of kidney problems caused by treatment with a certain anti-cancer drug (cisplatin). It is also used to help prevent a certain side effect (dry mouth) caused by radiation treatment for head and neck cancer. Amifostine is thought to work by preventing certain chemicals from damaging healthy cells. It may also help repair cells damaged by cisplatin or radiation treatment.


How to use AMIFOSTINE - INJECTION

HOW TO USE: This medication is given by injection into a vein by a health care professional, usually 15 to 30 minutes before cancer treatment or as directed by your doctor. Dosage is based on your medical condition, body size, and response to treatment. To decrease the risk of a certain side effect (low blood pressure), your doctor may direct you to lie down while receiving this medication. Also, if you are taking blood pressure medication, your doctor may direct you to stop taking it for 1 day before receiving this drug. Be sure to ask your doctor when to restart blood pressure medication. To decrease the risk of side effects (e.g., low blood pressure), drink plenty of fluids while using this medication unless otherwise directed by your doctor.

Side Effects

SIDE EFFECTS: Flushing, chills, unusual feelings of warmth/coldness, blurred vision, dizziness, drowsiness, or pain/redness/swelling at the injection site may occur. Nausea and vomiting occur frequently and can be severe. Your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, fast/slow/irregular heartbeat, muscle spasms, mental/mood changes, seizure. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before receiving amifostine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low/high blood pressure, dehydration, heart disease (e.g., irregular heartbeat, congestive heart failure), kidney disease, previous stroke. This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: blood pressure medications. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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AMIFOSTINE 500 MG VIAL
AMIFOSTINE 500 MG VIAL
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AMIFOSTINE 500 MG VIAL
AMIFOSTINE 500 MG VIAL
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ETHYOL 500 MG VIAL
ETHYOL 500 MG VIAL
ETHYOL 500 MG VIAL
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Faq for AMIFOSTINE - INJECTION

Amifostine Injection is used to prevent or reduce the side effects of certain cancer treatments, such as cisplatin chemotherapy or radiation therapy.

Amifostine Injection works by protecting normal cells from the harmful effects of cancer treatments. It helps prevent damage to organs such as the kidneys during chemotherapy or radiation.

Amifostine Injection is given as an intravenous (IV) infusion by a healthcare professional. The dosage and duration of treatment may vary depending on the specific cancer treatment being received.

The common side effects of Amifostine Injection can include nausea, vomiting, low blood pressure, flushing, and allergic reactions. Your healthcare provider will monitor you for these side effects during treatment.

Amifostine Injection may interact with certain medications, so it is important to inform your healthcare provider about all the medications you are taking. It is also important to tell your doctor if you have any pre-existing medical conditions, such as kidney problems.

It is important to follow your healthcare provider's instructions for the use of Amifostine Injection. This may include pre-medication to prevent certain side effects or following a specific schedule for administration.

Amifostine Injection should be used during pregnancy only if the potential benefits outweigh the potential risks. It is not known if Amifostine passes into breast milk, so it is recommended to avoid breastfeeding during treatment.

The coverage of Amifostine Injection by insurance plans may vary. It is recommended to check with your insurance provider to determine the coverage and any potential out-of-pocket costs.

Amifostine Injection may cause dizziness or low blood pressure, which can affect your ability to drive or operate machinery. It is recommended to talk to your healthcare provider about any potential restrictions or precautions.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.