ALOSETRON - ORAL

PHONETIC PRONUNCIATION: (al-OH-se-tron)

COMMON BRAND NAME(S): Lotronex

GENERIC NAME(S): alosetron HCl

Uses

USES: Alosetron is used to treat women with severe irritable bowel syndrome (IBS) who have diarrhea as the main problem. It is not a cure, but it may help to decrease abdominal pain, sudden urges to have a bowel movement, and diarrhea. This medication is not recommended for use by children because of the serious side effects that have been seen in adults.

How to use ALOSETRON - ORAL

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking alosetron and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. The dosage is based on your medical condition and response to treatment. Do not start taking this medication if you are constipated. Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

SIDE EFFECTS: See also Warning section. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Stop taking this medication and get medical help right away if any of these very serious side effects occur: constipation, bloody diarrhea/stools, new or worsening stomach/abdominal pain. This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, such as: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking alosetron, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: constipation, other bowel/intestinal disorders (such as bowel blockage, ischemic colitis, Crohn's disease, ulcerative colitis, diverticulitis), liver disease, blood clots. Before having surgery, tell your doctor or dentist about all the products you use (such as prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially constipation. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (such as prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: apomorphine, fluvoxamine. The risk of serious complications of constipation increases if you are also taking other drugs that may cause constipation. Ask your doctor or pharmacist about the safe use of all the products you may take. The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Some examples are street drugs such as MDMA/ "ecstasy," St. John's wort, certain antidepressants (such as SSRIs like fluoxetine/paroxetine, SNRIs like duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

ALOSETRON HCL 0.5 MG TABLET

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imprint: 54 628

ALOSETRON HCL 1 MG TABLET

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ALOSETRON HCL 0.5 MG TABLET

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shape: oblong
imprint: AN248

ALOSETRON HCL 1 MG TABLET

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imprint: AN249

ALOSETRON HCL 0.5 MG TABLET

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imprint: GX EX1

ALOSETRON HCL 1 MG TABLET

color: blue
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imprint: GX CT1

LOTRONEX 0.5 MG TABLET

color: white
shape: oblong
imprint: GX EX1

LOTRONEX 1 MG TABLET

color: blue
shape: oblong
imprint: GX CT1

ALOSETRON HCL 0.5 MG TABLET

color: white
shape: oblong
imprint: AN248

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Faq for ALOSETRON - ORAL

What is Alosetron used for

Alosetron is an oral medication used to treat irritable bowel syndrome with diarrhea (IBS-D) in women who have tried other treatments without success.

How does Alosetron work

Alosetron works by blocking the action of serotonin in the intestines. Serotonin is a chemical that affects bowel movements and can contribute to the symptoms of IBS-D.

What are the common side effects of Alosetron

Common side effects of Alosetron may include constipation, stomach discomfort or pain, nausea, headache, and dizziness. It is important to discuss any side effects with your doctor.

How long does it take for Alosetron to start working

Alosetron may take up to 4 weeks to start showing improvements in symptoms. It is important to continue taking the medication as prescribed by your doctor, even if you do not notice immediate relief.

Can men take Alosetron

Alosetron is currently only approved for use in women with IBS-D. It has not been studied or approved for use in men.

Can Alosetron be used during pregnancy

Alosetron is not recommended for use during pregnancy unless the potential benefits outweigh the risks. It is important to discuss the potential risks and benefits with your doctor if you are pregnant or planning to become pregnant.

Can Alosetron be used in children

Alosetron is not recommended for use in children under 18 years old. There is limited data available on the use of Alosetron in pediatric patients.

Are there any drug interactions with Alosetron

Certain medications may interact with Alosetron, including fluvoxamine, ciprofloxacin, erythromycin, and ketoconazole, among others. It is important to inform your doctor of all medications you are taking, including over-the-counter drugs and supplements.

Can Alosetron be used long-term

Alosetron is typically used as a short-term treatment for IBS-D. The duration of treatment may vary depending on the individual's response and the advice of their doctor. Long-term use of Alosetron may carry an increased risk of serious side effects.

ALOSETRON - ORAL Pricing Page Get Discount Coupon

Warning

WARNING: Alosetron has rarely caused serious, sometimes fatal side effects of the intestines. These effects include reduced blood flow to the large intestine (ischemic colitis) and serious complications of constipation. If you have constipation, new or worsening stomach/abdominal pain, or bloody diarrhea/stools, stop taking this medication and get medical help right away. If your constipation does not go away after stopping alosetron, again tell your doctor right away. Do not take this medication again unless your doctors tells you to do so. This medication should only be used by women with severe irritable bowel syndrome (IBS) whose main problem is diarrhea. Only carefully selected patients may use this medication. Consult your doctor or pharmacist for more information about the risks and benefits of using alosetron.

Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.