ALFUZOSIN EXTENDED-RELEASE - ORAL

ALFUZOSIN EXTENDED-RELEASE - ORAL

PHONETIC PRONUNCIATION: (al-FUE-zoe-sin)

COMMON BRAND NAME(S): Uroxatral

GENERIC NAME(S): alfuzosin HCl

Uses

USES: Alfuzosin is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night). Alfuzosin belongs to a class of drugs known as alpha blockers. Do not use this medication to treat high blood pressure.


How to use ALFUZOSIN EXTENDED-RELEASE - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking alfuzosin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily after a meal. This medication works best when taken with food. Taking alfuzosin on an empty stomach may make it not work as well. Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Alfuzosin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting, usually within a few hours after you take it. This risk is higher when you first start taking this drug or if you restart treatment after you stop taking it. During these times, avoid situations where you may be injured if you faint. To avoid injury from dizziness or fainting, your doctor may tell you to take your first dose of alfuzosin with food at bedtime so that your body can get used to its effects. Take this medication regularly to get the most benefit from it. To help you remember, take it after the same meal each day. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: Dizziness or lightheadedness may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, fast/irregular heartbeat, chest pain. Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking alfuzosin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, heart problems (such as chest pain/angina, heart attack), low blood pressure, certain eye problems (cataracts, glaucoma). Alfuzosin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using alfuzosin, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using alfuzosin safely. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery (including cataract/glaucoma eye surgery), tell your doctor or dentist if you are taking or have ever taken this medication, and about all the other products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially dizziness and low blood pressure when getting up from a sitting or lying position, and QT prolongation (see above). These side effects can also increase the risk of falling. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: other alpha blocker drugs (such as prazosin, terazosin). If you are also taking a drug to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may need to adjust your medications to minimize this risk. Other medications can affect the removal of alfuzosin from your body, which may affect how alfuzosin works. Examples include azole antifungals (such as itraconazole, ketoconazole), boceprevir, cobicistat, clarithromycin, nefazodone, HIV protease inhibitors (such as lopinavir, ritonavir), ribociclib, telaprevir, telithromycin, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.

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Faq for ALFUZOSIN EXTENDED-RELEASE - ORAL

Alfuzosin extended-release is used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH). It helps to relax the muscles in the prostate and bladder, which improves urinary flow and reduces the symptoms associated with BPH.

You should take Alfuzosin extended-release exactly as prescribed by your doctor. Usually, it is taken once daily, with food. It is important to swallow the tablet whole and not crush or chew it.

The common side effects of Alfuzosin extended-release may include dizziness, lightheadedness, headache, drowsiness, stomach pain, and decreased sexual ability. However, these side effects generally go away as your body adjusts to the medication.

It is important to inform your doctor about all the medications you are currently taking, as some drugs may interact with Alfuzosin extended-release. Particularly, you should avoid taking other alpha-blockers, certain antiarrhythmic medications, antifungal drugs, and protease inhibitors without consulting your doctor.

The onset of action of Alfuzosin extended-release can vary from person to person. However, it may take a few weeks for you to notice an improvement in your symptoms. It is important to continue taking the medication as prescribed, even if you do not see immediate results.

Drinking alcohol may increase certain side effects of Alfuzosin extended-release, such as dizziness and drowsiness. It is advisable to limit or avoid alcohol consumption while on this medication.

Alfuzosin extended-release is not approved for use in women and is specifically indicated for the treatment of BPH in men. Women should not take this medication.

If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Alfuzosin extended-release is not recommended for use in children. It is only approved for use in adults aged 18 years and older.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.