ADO-TRASTUZUMAB EMTANSINE - INJECTION
PHONETIC PRONUNCIATION: (tras-TOOZ-ue-mab em-TAN-seen)
COMMON BRAND NAME(S): Kadcyla
GENERIC NAME(S): ado-trastuzumab emtansine
USES: Ado-trastuzumab emtansine is used alone to treat certain types of breast cancer. This medication is used to treat tumors that produce more than the normal amount of a certain substance called HER2 protein. This medication is called a monoclonal antibody and microtubule inhibitor conjugate. Ado-trastuzumab emtansine works by attaching to the HER2 cancer cells and blocking them from dividing and growing. It may also destroy the cancer cells or signal the body (immune system) to destroy the cancer cells.
How to use ADO-TRASTUZUMAB EMTANSINE - INJECTION
HOW TO USE: See also Warning and Side Effects sections. Ado-trastuzumab emtansine may also be called trastuzumab emtansine. However, ado-trastuzumab emtansine is not the same as trastuzumab. Do not substitute trastuzumab for ado-trastuzumab emtansine. This medication is given by slow injection into a vein by a health care professional. It is given as directed by your doctor, usually once every 3 weeks. Your first infusion will be given over at least 90 minutes. The dosage, the speed of your injection, and the length of time you receive ado-trastuzumab emtansine is based on your body weight, medical condition, and response to treatment. To get the most benefit from this medication, do not miss any doses. To help you remember, mark the days on the calendar when you need to receive the medication. Your doctor may prescribe other medications (such as acetaminophen, diphenhydramine) for you to take before the start of your treatment to help prevent serious side effects.
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WARNING: Ado-trastuzumab emtansine has rarely caused very serious (possibly fatal) liver disease. Get medical help right away if you develop symptoms of liver disease, including persistent nausea, severe stomach/abdominal pain, dark urine, yellowing eyes/skin. Ado-trastuzumab emtansine may lead to serious heart problems, including heart failure. Past use of certain other anti-cancer drugs (including anthracyclines such as doxorubicin) may increase your risk of heart problems. Tell your doctor right away if you have any symptoms of heart failure, including shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain. Ado-trastuzumab emtansine can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Discuss reliable forms of birth control with your doctor. Do not substitute trastuzumab for ado-trastuzumab emtansine.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.