ACITRETIN - ORAL

PHONETIC PRONUNCIATION: (A-si-TRE-tin)

COMMON BRAND NAME(S): Soriatane

GENERIC NAME(S): acitretin

Uses

USES: This medication is a retinoid used in the treatment of severe psoriasis and other skin disorders in adults.

How to use ACITRETIN - ORAL

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start using acitretin and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist. Read and complete the Patient Agreement and Informed Consent document before taking this drug. Take this medication by mouth exactly as prescribed, usually once a day with your main meal. The dosage is based on your medical condition and response to therapy. Do not take this more often or increase your dose without consulting your doctor. Your condition will not improve any faster but the risk of side effects may increase. It may take 2 to 3 months before the full benefit of this medication is seen. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

Side Effects

SIDE EFFECTS: See also Warning section. You may experience more redness, itching, skin scaling, peeling and dry skin the first several weeks as your body adjusts to the medication. Dry eyes, eye irritation, crusting of the eye lids, dry mouth, peeling of the skin of fingertips, palms or soles of feet, chapped lips, runny nose, thirst, taste changes and hair loss may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Contact lens wearers may be uncomfortable while taking this drug because it causes dry eyes. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: decreased night vision, fever, chills, dizziness, aches and pain in the bones or joints, muscle pain/tenderness/weakness, difficulty moving, swelling, sudden weight gain, signs of kidney problems (such as change in the amount of urine). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking acitretin, tell your doctor or pharmacist if you are allergic to it; or to vitamin A-related drugs (other retinoids such as isotretinoin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, heart disease, diabetes, personal or family history of mental/mood problems (such as depression), receive phototherapy. Do not donate blood while taking this drug and for at least 3 years after stopping therapy. This will prevent the possibility of your blood being given to a pregnant woman. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Acitretin may cause vision changes, including decreased night vision. Do not drive, use machinery, or do any activity that requires clear vision (especially at night) until you are sure you can perform such activities safely. Avoid drinking alcohol while taking this medication and for 2 months after stopping it. This drug must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor right away. This drug should not be used if you are planning to become pregnant during treatment or within 3 years after use has stopped. Use 2 effective forms of birth control starting 1 month before and during treatment and at least 3 years after use has stopped. If you are unsure which types of birth control are effective, consult your doctor, pharmacist, or Medication Guide. Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules. Semen may pose a risk to a pregnant woman if a male is using this drug. Consult your doctor. It is not known if this drug is excreted into breast milk. Breast-feeding is not recommended while using this medication and for at least three years after the medication has been stopped.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: methotrexate, St. John's wort, tetracycline antibiotics, vitamin A.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include severe headache, nausea, vomiting, drowsiness, irritability, loss of balance, and itching.

Images

ACITRETIN 10 MG CAPSULE

color: light green
shape: oblong
imprint: TEVA, 1135

ACITRETIN 25 MG CAPSULE

color: light green
shape: oblong
imprint: TEVA, 1136

ACITRETIN 17.5 MG CAPSULE

color: yellow
shape: oblong
imprint: TEVA, 1138

ACITRETIN 17.5 MG CAPSULE

color: yellow
shape: oblong
imprint: WPI, 2264

ACITRETIN 25 MG CAPSULE

color: yellow
shape: oblong
imprint: WPI, 2266

ACITRETIN 10 MG CAPSULE

color: white
shape: oblong
imprint: 667, IX

ACITRETIN 25 MG CAPSULE

color: yellow
shape: oblong
imprint: IX, 669

SORIATANE 10 MG CAPSULE

color: white
shape: oblong
imprint: A-10 mg, A-10 mg

SORIATANE 25 MG CAPSULE

color: yellow
shape: oblong
imprint: A-25mg, A-25mg

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Faq for ACITRETIN - ORAL

What is acitretin used for

Acitretin is prescribed to treat severe cases of psoriasis, a chronic skin condition characterized by red, scaly patches on the skin.

How does acitretin work

Acitretin belongs to a class of medications called retinoids. It works by suppressing the growth of skin cells and reducing inflammation, which helps to control the symptoms of psoriasis.

How long does it take for acitretin to work

The effects of acitretin can be seen within 2 to 4 weeks of starting treatment. However, significant improvement in psoriasis symptoms may take several months.

What are the common side effects of acitretin

The common side effects of acitretin include dry skin, chapped lips, dry eyes, hair loss, increased sensitivity to sunlight, muscle and joint pain, and elevated cholesterol and triglyceride levels. It is important to report any severe or persistent side effects to your doctor.

How should acitretin be taken

Acitretin should be taken exactly as prescribed by your doctor. Usually, it is taken once daily with food or a high-fat meal to enhance its absorption. It is essential to avoid alcohol during treatment with acitretin as it can increase the risk of serious liver problems.

Can acitretin be taken during pregnancy

No, acitretin should not be taken during pregnancy or if there is a possibility of becoming pregnant. It can cause severe birth defects, and women of childbearing age are required to use effective contraception both during and for three years after stopping the medication.

Can acitretin interact with other medications

Yes, acitretin may interact with certain medications, including oral contraceptives, tetracycline antibiotics, methotrexate, and certain psychiatric medications. It is important to inform your doctor about all the medications you are taking to avoid potential drug interactions.

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Warning

WARNING: Do not use this medication if you are pregnant or planning to become pregnant within 3 years of stopping this drug because it has caused serious birth defects. Use 2 effective birth control methods starting 1 month before taking this medication and at least 3 years after treatment has stopped. Do not use "minipills" (non-estrogen-containing pills) for birth control because they may not work as well with this drug. Females who are able to have children must not use this medication unless the following requirements are met: test negative on 2 pregnancy tests (they should be taken 1 week before starting this drug or at least 11 days after the last act of unprotected sexual intercourse); start therapy within 7 days of taking the second pregnancy test; present severe psoriasis and other treatments cannot be used; receive oral and written information on using 2 methods of birth control while taking this drug and for 3 years after stopping it; aware of the dangers of birth control failure and use during pregnancy; understand and correctly follow all birth control requirements and instructions including monthly pregnancy tests during treatment and every 3 months for 3 years after treatment has stopped. Do not drink alcohol while using acitretin and for 2 months after stopping it because alcohol causes this drug to stay in the body longer. It is not known if traces of this drug found in semen of male patients pose a risk to the unborn baby during use or after treatment has stopped. Acitretin may rarely cause serious (possibly fatal) liver disease (hepatitis) and increased fluid pressure on the brain (pseudotumor cerebri). If you notice any of the following unlikely but serious side effects, get medical help right away: yellowing eyes/skin, dark urine, persistent nausea/vomiting/loss of appetite, severe stomach/abdominal pain, unusual tiredness, persistent/severe headache, or vision changes (such as blurred/double vision, decreased vision). Acitretin has also been linked to pancreatitis (inflammation of the pancreas). Notify your doctor right away if you develop persistent, lower abdominal pain. Rarely, acitretin may cause serious mental/mood changes, even after stopping the medication. Get medical help right away if you have symptoms such as depression, irritability, aggressive or violent behavior, or thoughts of suicide.

Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.