ABIRATERONE (SUBMICRONIZED) - ORAL

ABIRATERONE (SUBMICRONIZED) - ORAL

PHONETIC PRONUNCIATION: (A-bir-A-ter-one)

COMMON BRAND NAME(S): Yonsa

GENERIC NAME(S): abiraterone acetate, submicronized

Uses

USES: This medication is used to treat men with prostate cancer. Abiraterone belongs to a class of drugs known as anti-androgens (anti-testosterone). Testosterone, a natural hormone, helps prostate cancer to grow and spread. Abiraterone works by blocking the production of testosterone, which helps slow down the growth and spread of prostate cancer. This medication should not be used by women or children.


How to use ABIRATERONE (SUBMICRONIZED) - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking abiraterone and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Different brands of this medication may have different dosing directions. Do not change brands of this medication without your doctor's direction. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Swallow this medication whole with water. Do not crush or chew the tablets. The dosage is based on your medical condition, lab results, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase. Tell your doctor if your condition gets worse (such as urination becomes more difficult, bone pain increases). Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

Side Effects

SIDE EFFECTS: Headache, hot flushes, joint pain, heartburn, or cold-like symptoms may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Your doctor may control your blood pressure with medication. Tell your doctor right away if you have any serious side effects, including: increased urination, painful urination, fast/irregular heartbeat, muscle cramps/weakness, leg pain, swelling in legs/feet, bone fractures. Get medical help right away if you have any very serious side effects, including: chest pain, feeling short of breath while at rest, symptoms of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking abiraterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart failure, irregular heartbeat, previous heart attack), high blood pressure, liver problems. Using corticosteroid medications for a long time along with abiraterone can make it more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets. This medication should not be used by women, especially during pregnancy or breast-feeding. It may harm an unborn or breast-feeding baby. Consult your doctor for more details. Because it is unknown if abiraterone passes into semen, men with a pregnant female partner must use a latex condom during all sexual contact, even if they have had a vasectomy. Men with female partners of childbearing age should use a latex condom and another reliable form of birth control (such as diaphragm with spermicide) while taking this medication and for at least 3 weeks after stopping treatment.

Interactions

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for ABIRATERONE (SUBMICRONIZED) - ORAL

Abiraterone (submicronized) - Oral is used to treat metastatic prostate cancer that has not responded to other treatments.

Abiraterone (submicronized) - Oral is an androgen biosynthesis inhibitor that works by blocking the production of certain hormones necessary for the growth of prostate cancer cells.

Abiraterone (submicronized) - Oral is usually taken once a day on an empty stomach, at least one hour before or two hours after eating. It should be swallowed whole with water and not crushed or chewed.

Common side effects of Abiraterone (submicronized) - Oral may include fatigue, joint pain, hot flashes, diarrhea, nausea, swelling in the legs or feet, high blood pressure, and abnormal liver function tests.

Serious side effects of Abiraterone (submicronized) - Oral may include adrenal insufficiency, bone fractures, liver problems, and increased levels of certain enzymes in the blood. It is important to seek immediate medical attention if you experience severe abdominal pain, dark urine, yellowing of the skin or eyes, or unusual fatigue.

Abiraterone (submicronized) - Oral may lower your sex drive and cause erectile dysfunction. It is recommended to discuss any concerns or changes in sexual function with your doctor or healthcare provider.

Abiraterone (submicronized) - Oral may interact with certain medications, including blood thinners, cholesterol-lowering drugs, and drugs that affect heart rhythm. It is important to inform your doctor or pharmacist about all the medications you are taking before starting Abiraterone (submicronized) - Oral.

Abiraterone (submicronized) - Oral is not intended for use in women or children and should only be used by adult men as prescribed by their healthcare provider.

The duration of treatment with Abiraterone (submicronized) - Oral will depend on your individual response to the medication and the progression of your cancer. Your doctor will determine the appropriate duration and dosing schedule for you.

Abiraterone (submicronized) is a medication used in the treatment of prostate cancer. It belongs to a class of drugs known as androgen synthesis inhibitors. It works by inhibiting the production of androgens (male hormones) in the body, which can help slow down the growth of prostate cancer cells.

Common side effects of Abiraterone (submicronized) may include fatigue, joint pain, fluid retention, hot flashes, increased blood pressure, upset stomach, and diarrhea. It is important to inform your doctor if you experience any persistent or severe side effects.

Abiraterone (submicronized) is taken orally in the form of tablets. It is typically taken once a day on an empty stomach, at least one hour before or two hours after a meal. The dosage and duration of treatment will be determined by your doctor.

Abiraterone (submicronized) may interact with other medications, including certain antifungal drugs, HIV medications, and medications that affect liver enzymes. It is important to inform your doctor about all the medications you are taking, including prescription, over-the-counter, and herbal products, before starting Abiraterone (submicronized).

Yes, Abiraterone (submicronized) may cause adrenal insufficiency, a condition where the adrenal glands do not produce enough hormones. It is important to have regular blood tests to monitor your hormone levels. Abiraterone (submicronized) may also cause liver toxicity, so regular liver function tests are recommended.

Abiraterone (submicronized) is not indicated for use in women and should not be taken during pregnancy. It can cause harm to an unborn baby. Women who are pregnant or planning to become pregnant should avoid any contact with the medication.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.