ABALOPARATIDE - INJECTION

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ABALOPARATIDE - INJECTION

PHONETIC PRONUNCIATION: (a-BAL-oh-PAR-a-tide)

COMMON BRAND NAME(S): Tymlos

GENERIC NAME(S): abaloparatide

Uses

USES: Abaloparatide is used to treat bone loss (osteoporosis) for women after menopause who are at high risk of having broken bones (fractures). It is similar to a natural hormone in your body (parathyroid hormone). It works by increasing bone density and strength. This effect helps to decrease the risk of having a fracture. This medication should not be used for children or young adults whose bones are still growing.


How to use ABALOPARATIDE - INJECTION

HOW TO USE: Read the Medication Guide and Instructions For Use provided by your pharmacist before you start using abaloparatide and each time you get a refill. If you have any questions, ask your doctor or pharmacist. If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Inject this medication under the skin of the abdomen area as directed by your doctor, usually once daily. When you give the first several doses, make sure you are in a place where you can sit or lie down if you have dizziness. Learn how to store and discard medical supplies safely. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

Side Effects

SIDE EFFECTS: Dizziness or fast heartbeat may occur within 4 hours after using this medication. If these effects occur, sit or lie down right away. These symptoms usually go away within a few hours. These effects should go away after several doses as your body adjusts to the medication. Redness/pain/swelling at the injection site may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: signs of a high level of calcium in the blood (such as nausea, vomiting, constipation, unusual tiredness, muscle weakness, mental/mood changes including confusion). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: See also Warning section. Before using abaloparatide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: other bone disorders (such as bone cancer), high level of calcium in the blood, kidney stones, kidney disease, high level of parathyroid hormone. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication is not usually used in women of childbearing age. It is unlikely to be used during pregnancy or breast-feeding. Consult your doctor if you have any questions about this medication.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: nausea, vomiting, severe dizziness, unusual tiredness, headache.

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Faq for ABALOPARATIDE - INJECTION

Abaloparatide is used to treat osteoporosis in postmenopausal women at a high risk of fracture.

Abaloparatide is a synthetic form of a naturally occurring hormone called parathyroid hormone-related protein (PTHrP). It works by increasing bone formation and promoting the growth of new bone.

Common side effects of Abaloparatide may include headache, dizziness, nausea, leg cramps, and injection site reactions such as pain or swelling.

Abaloparatide is given as a subcutaneous injection (under the skin) once daily. It is important to follow the instructions provided by your healthcare provider.

You should inform your healthcare provider about any other medications you are taking, especially if you are already using any other osteoporosis treatments. It is also important to inform your doctor if you have a history of certain medical conditions such as increased levels of calcium in the blood or kidney stones.

Abaloparatide treatment is typically prescribed for 18 months. It is important to continue the treatment as instructed by your healthcare provider to get the full benefits.

No, Abaloparatide is only approved for use in postmenopausal women at a high risk of fracture.

Abaloparatide may interact with certain medications, including drugs that affect calcium levels in the blood. It is important to inform your healthcare provider about any other medications you are taking.

While Abaloparatide is generally well-tolerated, long-term risks of treatment are not fully known. It is important to discuss the potential benefits and risks of treatment with your healthcare provider.

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Warning

WARNING: Abaloparatide has been shown to increase bone tumors (osteosarcoma) in rats. However, this occurred at doses higher than the usual human dose. It is unknown if this medication can cause bone tumors in humans. This medication should not be used if you have an increased risk for bone tumors (including if you have Paget's disease of bone or if you have had radiation treatment involving the bones). Discuss the details and the benefits and risks of this medication with your doctor before starting treatment.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.