Vivitrol: A Comprehensive Guide Vivitrol (naltrexone) is a medication that is effective in reducing the symptoms of alcohol or opioid dependence by blocking the effects of drugs of abuse. It is a non-addictive, long-acting, and extended-release formulation of naltrexone that is administered by injection. This article will provide an in-depth look at the uses, dosage, demographic, side effects, interactions, and generic options of Vivitrol. Uses Vivitrol is approved by the U.S. Food and Drug Administration for the treatment of alcohol dependence and opioid dependence. It works by inhibiting the action of endorphins, the natural opioids that the body produces, which reduces the euphoria or high associated with alcohol or opioid use. Vivitrol also reduces cravings for these substances, which can lead to abstinence and recovery from addiction. Dosage The recommended dosage of Vivitrol is 380 mg administered once every four weeks as an intramuscular injection. It is important to receive the injection from a healthcare professional who is trained in its administration. Before receiving Vivitrol, it is important to abstain from alcohol and drugs, including opioids, for a minimum of seven to 10 days to avoid precipitating acute withdrawal symptoms. Demographic Vivitrol is indicated for adults over the age of 18 who are dependent on alcohol or opioids. It may be appropriate for individuals who have completed detoxification and are motivated to maintain abstinence. Vivitrol is not recommended for individuals who have a current or recent history of liver or kidney disease, acute hepatitis, or hypersensitivity to naltrexone. Side Effects The most common side effects of Vivitrol include injection site reactions, such as pain, swelling, or redness, which typically resolve within a few days to a week after treatment. Other common side effects include nausea, headache, dizziness, fatigue, and insomnia. Rarely, Vivitrol may cause severe liver damage, especially in individuals with pre-existing liver disease, so regular liver function tests are recommended. Interactions Vivitrol may interact with other medications, including other medications that act on the central nervous system, such as antidepressants or antipsychotics. Vivitrol may also lower the threshold for seizures in some individuals. Before starting Vivitrol, it is important to inform your healthcare provider of all medications you are taking, including over-the-counter medications, supplements, and vitamins. Generic Options Currently, there are no generic versions of Vivitrol available. However, the generic medication naltrexone is also used to treat alcohol and opioid dependence. Naltrexone is available as an oral tablet or as an extended-release injection that is administered once per month. While naltrexone is not a replacement for Vivitrol, it may be a more affordable option for some individuals. Conclusion Vivitrol is a medication that is used to treat alcohol and opioid dependence. It is administered once per month as an intramuscular injection and works by reducing euphoria and cravings associated with substance use. While Vivitrol is generally well-tolerated, it may cause side effects or interact with other medications. It is important to speak with your healthcare provider to determine whether Vivitrol or another medication is right for you.