Valchlor: A Comprehensive Guide on Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Introduction Valchlor, also known by its generic name Mechlorethamine, is a nitrogen mustard alkylating agent used to treat stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have not responded to other treatments. In this article, we will discuss the uses, dosage, demographic, side effects, interactions, and generic options of Valchlor in detail. Uses of Valchlor Valchlor is primarily used to treat stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have not responded to other treatments. This medication works by killing cancer cells and slowing down their growth rate. It is applied topically to the skin on a regular basis and is specifically designed to target cancerous cells while sparing healthy skin. Dosage of Valchlor The dosage of Valchlor depends on the patient's weight and the severity of their condition. The recommended starting dose for adults is 0.0166 mg/cm² of body surface area, applied once daily. The dose may be increased to a maximum of 0.0222 mg/cm² of body surface area, applied once daily. Patients should not apply more than 200 mg/dose or 2,000 mg/week. Demographic for Valchlor Valchlor is primarily used to treat mycosis fungoides-type cutaneous T-cell lymphoma in adults. It is not recommended for use in children or adolescents. Patients who are pregnant or breastfeeding should speak with their doctor before using Valchlor. Side Effects of Valchlor Valchlor can cause various side effects, including skin reactions, gastrointestinal symptoms, hematologic changes, and hypersensitivity reactions. The most common side effect of this medication is skin reactions, which include redness, itching, burning, and the formation of blisters or ulcers. Other side effects may include nausea, vomiting, diarrhea, fatigue, anemia, leukopenia, thrombocytopenia, and allergic reactions. Patients who experience persistent or severe side effects should contact their doctor immediately. Interactions of Valchlor Valchlor may interact with other medications or supplements the patient may be taking. Patients should consult their doctor or pharmacist before taking any new medications or supplements, including over-the-counter medications. Generic Options of Valchlor Valchlor is the brand name for Mechlorethamine gel. There are no generic equivalents available for Valchlor at this time. However, a compounding pharmacy may be able to create a similar product for patients who require a lower cost option. Conclusion Valchlor is a medication used to treat stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have not responded to other treatments. It is applied topically to the skin on a regular basis and is specifically designed to target cancerous cells while sparing healthy skin. The recommended dosage depends on the severity of the patient's condition, and side effects may include skin reactions, gastrointestinal symptoms, hematologic changes, and hypersensitivity reactions. Patients should always consult their doctor or pharmacist before taking any new medications or supplements, including over-the-counter medications. Although there are no generic options available for Valchlor, a compounding pharmacy may be able to create a similar product for patients who require a lower cost option.