Sustiva: Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Sustiva is a brand-name medication that contains the active ingredient efavirenz. Its primary purpose is to treat human immunodeficiency virus (HIV) infection. Uses: Sustiva is used in combination with other medications to treat HIV infection in adults and children who weigh more than 40 kilograms (88 lbs). It belongs to the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of drugs that work by blocking the HIV enzyme reverse transcriptase, which is necessary for the virus to multiply. Dosage: The recommended dosage of Sustiva for adults is 600 milligrams (mg) taken orally once a day at bedtime. For children weighing at least 40 kg, the dosage is the same as that of adults. However, for children weighing 20-40 kg, the dosage is based on weight and divided into two daily doses. Demographic: Sustiva is mainly prescribed for adults living with HIV-1. However, it is also used in children aged three months and older who are living with HIV-1 and are not able to tolerate other medications or have not responded well to them. Side Effects: Like all medications, Sustiva has some potential side effects. Some of the most common ones are: - Dizziness - Headache - Insomnia - Fatigue - Rash - Nausea - Vomiting - Diarrhea - Abnormal dreams or nightmares Less commonly, Sustiva can cause more serious side effects, including: - Depression - Suicidal thoughts or behaviors - Seizures - Changes in liver function - Changes in body fat distribution Patients who experience any of these symptoms should seek medical attention immediately. Interactions: Sustiva can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications that may interact with Sustiva include: - Anti-anxiety medications - Anti-seizure medications - Blood thinners - Cholesterol-lowering medications - Erectile dysfunction medications Patients should always inform their healthcare provider of any medications they are taking before starting Sustiva to prevent potentially harmful interactions. Generic options: Sustiva is only available as a brand-name medication, and there is currently no generic version of efavirenz available in the United States. However, patients may be able to find generic versions of the medication in other countries. In conclusion, Sustiva is a medication used in combination with others to treat HIV-1 infection in adults and children. Patients should follow the recommended dosage and contact their healthcare provider immediately if they experience any serious side effects. Additionally, it is important to disclose any other medications or supplements being taken to prevent possible drug interactions. While there is currently no generic option available in the US, patients may be able to find generic versions of the medication in other countries.