Sprix: A Complete Guide to Uses, Dosage, Demographic, Side Effects, Interactions and Generic Options What is Sprix? Sprix (ketorolac tromethamine) is a nonsteroidal anti-inflammatory drug (NSAID) that is available as a nasal spray. It is commonly used to relieve pain, inflammation and fever. Ketorolac tromethamine is a potent analgesic that works by inhibiting the production of prostaglandins, which are the substances in the body responsible for pain, inflammation and fever. Uses Sprix is commonly used to relieve pain, inflammation and fever associated with the following conditions: - Dental pain - Headache - Migraine - Bursitis - Tendinitis - Soft tissue injuries - Post-operative pain - Rheumatoid arthritis - Osteoarthritis Dosage Sprix nasal spray is available in 15.75 mg strength. For adults, the usual dose is one spray in each nostril every 6-8 hours, not to exceed 4 sprays per day or a total of 56 mg per day. The maximum recommended duration of treatment with Sprix is five days. Demographic Sprix is approved for use in adults only and should not be used in children. It should also be used with caution in the elderly and in patients with a history of asthma, bleeding disorders, liver or kidney disease, heart disease, high blood pressure or a previous allergic reaction to NSAIDs. Side Effects Like all medications, Sprix can cause side effects, although not everyone will experience them. Common side effects of Sprix include: - Nasal irritation - Burning or stinging sensation in the nose - Headache - Dizziness - Nausea - Vomiting - Rash Rare but serious side effects that can occur with Sprix include: - Anaphylaxis (severe allergic reaction) - Gastrointestinal bleeding - Kidney failure - Liver damage - Heart attack or stroke Interactions Sprix can interact with other medications, so it is important to inform your doctor if you are taking any other medications, including prescription, over-the-counter, or herbal remedies. Sprix should not be used at the same time as other NSAIDs, such as aspirin, ibuprofen, and naproxen, as it may increase the risk of side effects. Sprix may also interact with blood thinners, corticosteroids, and selective serotonin reuptake inhibitors (SSRIs). Generic Options Ketorolac tromethamine is the generic name for Sprix. There are other ketorolac formulations available, including tablets and injections, which are sold under different brand names. Ketorolac tablets are available under the brand names Toradol and Acular, while ketorolac injections are marketed under the brand name Toradol. These formulations are used to treat different types of pain or inflammation and may have different dosing requirements. Conclusion Sprix is a nasal spray formulation of ketorolac tromethamine, a potent NSAID that is used to relieve pain, inflammation, and fever. It is approved for use in adults only and should not be used in children. The usual dose is one spray in each nostril every 6-8 hours, not to exceed 4 sprays per day or 56 mg per day, for a maximum of five days. It is important to be aware of the potential side effects and drug interactions of Sprix and to inform your doctor of any other medications you are taking. If you experience any unusual or severe side effects, seek medical attention right away.