Simbrinza is a prescription medication used to treat open-angle glaucoma or ocular hypertension. It is a combination drug that contains two active ingredients – brinzolamide and brimonidine tartrate. Brinzolamide is a carbonic anhydrase inhibitor that reduces the amount of fluid produced in the eye, while brimonidine tartrate is an alpha-2-adrenergic receptor agonist that decreases the pressure in the eye. Uses of Simbrinza Simbrinza is used to treat open-angle glaucoma or ocular hypertension. It is used to lower eye pressure, which can help prevent damage to the optic nerve and vision loss. Dosage of Simbrinza The recommended dosage of Simbrinza is one drop in the affected eye(s) twice a day, with approximately 12 hours between doses. The medication should be used exactly as prescribed by the doctor. The drop should be gently instilled into the eye and one should avoid touching the dropper to the eye or any other surface. Demographic Simbrinza is approved for use in adults over the age of 18. The medication has not been studied in children and its use in this group is not recommended. Side Effects of Simbrinza Simbrinza may cause side effects in some people. The most common side effects include blurred vision, eye redness, eye itching or burning, eye irritation, dry mouth, taste changes, and headaches. These side effects usually go away on their own over time. However, if any of these side effects persist or worsen, it is important to contact the doctor immediately. Serious side effects of Simbrinza are quite rare but may include allergic reactions to the medication like hives, difficulty breathing, and swelling of the face, lips, tongue, or throat, or eye infections like conjunctivitis or eye discharge. Interactions Simbrinza may interact with other medications. One should inform their doctor about all the prescription and non-prescription medications, vitamins, and supplements they are taking before using Simbrinza. Mentioning any glaucoma medications including oral and topical ones, and some medications used to treat high blood pressure, depression, or heart disease is specifically important. Generic Options Simbrinza is a combination medication that has no generic equivalents. However, its two individual components, brinzolamide and brimonidine tartrate, are each available in generic form. Conclusion Simbrinza is an effective medication for the treatment of open-angle glaucoma or ocular hypertension. It contains two active ingredients, brinzolamide and brimonidine tartrate, which work together to decrease the pressure in the eye. Simbrinza is taken twice a day, with approximately 12 hours between doses. It may cause side effects in some people, but they are usually mild and go away on their own over time. It is important to inform one's doctor about all the medications they are currently taking and any medical conditions before using Simbrinza.