Sensipar: A Comprehensive Guide on Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Sensipar is a medication used to treat hyperparathyroidism in patients with chronic kidney disease (CKD) and parathyroid carcinoma. It is a calcium-sensing receptor agonist that helps regulate the level of calcium in the blood by blocking the parathyroid hormone. Uses Sensipar is indicated for the treatment of secondary hyperparathyroidism (SHPT) in adult patients with CKD on dialysis and for the treatment of hypercalcemia in patients with parathyroid carcinoma. SHPT is a common complication of CKD that affects the bones and mineral balance in the body. Sensipar helps lower parathyroid hormone levels and reduce the risk of bone disease, fractures, and other complications associated with SHPT. Dosage The recommended starting dose of Sensipar for patients on dialysis with SHPT is 30 mg once daily. The dose may be increased by 30 mg every 2-4 weeks as needed to achieve target levels of intact parathyroid hormone (iPTH), usually between 150 and 300 pg/mL. The maximum daily dose should not exceed 180 mg/day. For patients with parathyroid carcinoma, the starting dose of Sensipar is 30 mg three times daily, which may be increased by 30 mg every 2-4 weeks as needed. The maximum daily dose should not exceed 90 mg/day. Demographic Sensipar is approved for use in adult patients with CKD on dialysis and in patients with parathyroid carcinoma. The medication is not recommended for use in children. Side Effects Like all medications, Sensipar may cause side effects. Common side effects include nausea, vomiting, diarrhea, and loss of appetite. These side effects may be reduced by taking Sensipar with food. Other possible side effects include headache, dizziness, and decreased serum calcium levels. In rare cases, Sensipar may cause serious side effects, such as seizures, heart failure, and hypoparathyroidism. Patients should seek medical attention immediately if they experience symptoms such as chest pain, difficulty breathing, seizures, or tingling in the hands or feet. Interactions Sensipar may interact with other medications, such as calcium supplements, vitamin D supplements, and certain antifungal drugs. Patients should inform their healthcare providers of all medications they are taking before starting Sensipar. Sensipar may also interact with certain medical conditions, such as hypocalcemia and liver disease. Generic Options Sensipar is the brand name for the generic drug cinacalcet. Cinacalcet is available in different formulations and brand names, including Compentia, Sensipar, and Mimpara. Patients may choose between brand name and generic options depending on availability and cost. Conclusion Sensipar is a medication used to treat secondary hyperparathyroidism in patients with chronic kidney disease on dialysis and for the treatment of hypercalcemia in patients with parathyroid carcinoma. The medication helps regulate calcium levels in the blood and reduce the risk of bone disease, fractures, and other complications associated with SHPT. Patients should inform their healthcare providers of all medications they are taking before starting Sensipar. While Sensipar may cause side effects, they are typically mild and can be managed with proper dosing and instruction. Patients may choose between brand name and generic options depending on availability and cost.