Rifater (rifampin, isoniazid, and pyrazinamide) is a combination of three anti-tuberculosis drugs that are used to treat tuberculosis (TB) in adults. As a potent antibiotic, Rifater essentially works by inhibiting the growth and multiplication of TB-causing microorganisms in the body. Rifater is generally prescribed for the treatment of tuberculosis in adults, particularly those who are experiencing active TB infection or who have latent TB infections. According to the U.S. Centers for Disease Control and Prevention (CDC), Rifater is most commonly prescribed as a first-line therapy for multidrug-resistant TB. Dosage and Administration The dosage of Rifater depends on the individual patient's condition and their medical history. In general, the recommended adult dose for the treatment of active TB is two tablets of Rifater (300mg rifampin, 150mg isoniazid, and 750mg pyrazinamide) twice daily for two months followed by two tablets of Rifinah (300mg rifampin and 150mg isoniazid) once daily for another four months. It is important to note that Rifater should be taken with a full glass of water and should not be crushed, chewed, or broken. Additionally, patients taking Rifater should not consume alcohol as it may increase the risk of liver damage and other side effects. Demographic Information Rifater is typically prescribed for adults who have active TB infections or latent TB infections. However, it is not recommended for use in children or pregnant women due to the potential risk of liver damage and other side effects. Side Effects As with any medication, Rifater may cause side effects in some patients. The most common side effects of Rifater include: - Nausea - Vomiting - Upset stomach - Headache - Dizziness - Fatigue - Abdominal discomfort - Skin rash In rare cases, Rifater may cause more serious side effects such as liver toxicity or a blood disorder called hemolytic anemia. If you experience any symptoms of liver toxicity, such as yellowing of the skin or eyes, dark urine, or abdominal pain, you should contact your healthcare provider immediately. Interactions Rifater may interact with other medications, including birth control pills, blood thinners, and HIV medications. Patients should inform their healthcare provider of all medications they are currently taking before starting treatment with Rifater. Generic Options There are currently no generic versions of Rifater available in the United States. However, there are generic versions of the individual ingredients in Rifater, which may be less expensive than the brand-name version. Conclusion Overall, Rifater is a potent antibiotic that is commonly prescribed for the treatment of tuberculosis in adults. Patients taking Rifater should be aware of potential side effects and should inform their healthcare provider of all medications they are currently taking. While there are currently no generic versions of Rifater available in the United States, there are generic versions of the individual ingredients in Rifater which may be less expensive.