Restasis: Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Restasis is an ophthalmic emulsion that helps increase the production of tears in patients with chronic dry eye. It contains cyclosporine, an immunosuppressant agent that reduces inflammation in the eyes. In this article, we will discuss the uses, dosage, demographic, side effects, interactions, and generic options of Restasis. Uses Restasis is primarily used to treat chronic dry eye disease, a condition where a patient experiences a persistent lack of moisture in the eyes. It is estimated that 16 million adults in the United States suffer from this condition. Chronic dry eye can cause symptoms such as eye redness, burning, itching, and blurry vision. Restasis is also used to treat patients who have undergone LASIK, a vision correction surgery that can cause dry eye as a side effect. Restasis can reduce the risk of corneal damage in these patients. In addition, Restasis can be used to treat inflammation in the eyes caused by other eye diseases such as meibomian gland dysfunction (MGD) and ocular rosacea. Dosage Restasis is available as a 0.05% emulsion and is prescribed as one drop in each eye twice daily, about 12 hours apart. Improvement in symptoms may take a few weeks to a few months, depending on the severity of the condition. Before using Restasis, patients should thoroughly wash their hands and avoid touching the tip of the dropper to the eye or any other surface. They should also remove their contact lenses before using Restasis and wait 15 minutes before reinserting them. Demographic Restasis is approved for use in adults only and is not recommended for use during pregnancy or breastfeeding. Patients with a history of herpes infection in the eyes should also avoid using Restasis. The safety and effectiveness of Restasis in children under 16 years old have not been established. Side Effects The most common side effects of Restasis are burning, stinging, and itching in the eyes. Other side effects may include blurred vision, redness, foreign body sensation, and tearing. These side effects usually resolve within a few weeks of starting treatment. In rare cases, Restasis can cause serious side effects such as eye infections, corneal ulcers, and conjunctivitis. Patients should contact their healthcare provider immediately if they experience any of these symptoms. Interactions Restasis is metabolized by enzymes in the liver and can interact with other medications that also use these enzymes. Patients taking medications such as rifampin, phenytoin, or carbamazepine should inform their healthcare provider before starting Restasis. Patients should also avoid using other eye drops or ointments at the same time as Restasis unless instructed by their healthcare provider. Generic Options While there is no generic version of Restasis currently available, a cheaper alternative called Cequa was approved by the FDA in 2019. Cequa contains the same active ingredient as Restasis and has been shown to be equally effective in treating chronic dry eye. Conclusion Restasis is a well-established treatment option for patients with chronic dry eye disease that can help increase tear production and reduce inflammation. While it is generally safe and effective, patients should be aware of the potential side effects and drug interactions. At present, there is no generic version of Restasis, but Cequa offers a more affordable alternative. Ultimately, patients should consult with their healthcare provider to determine the most appropriate treatment plan for their individual needs.