Proleukin (also known as Aldesleukin) is a medication used in the treatment of certain types of cancer, typically melanoma and renal cell carcinoma. This medication is a type of interleukin-2, which is a protein that occurs naturally in the body and is responsible for regulating immune system function. Proleukin works by stimulating the immune system to attack cancer cells. Uses Proleukin is indicated for the treatment of metastatic melanoma and metastatic renal cell carcinoma. This medication is typically given to patients who have not responded to other cancer treatments. Proleukin works by stimulating the body's immune system to attack cancer cells, which can help to slow the progression of the disease. Dosage The dosage of Proleukin will depend on the patient's weight, overall health, and the type of cancer being treated. Proleukin is typically given by infusion into a vein, and the treatment course can last for several weeks. Patients may require multiple rounds of treatment, and the dose may be adjusted depending on how the patient responds to the medication. Demographic Proleukin is typically used in adults over the age of 18 who have been diagnosed with metastatic melanoma or metastatic renal cell carcinoma. This medication is not typically used in pediatric populations. It is also not recommended for use in patients with a history of heart disease, kidney disease, or seizures. Side Effects Like all medications, Proleukin can cause side effects. Some of the most common side effects include fever, chills, nausea, vomiting, diarrhea, fatigue, and weakness. These side effects are typically mild to moderate in severity and can be managed with supportive care. More serious side effects include low blood pressure, fast or irregular heartbeat, trouble breathing, confusion, and seizures. Patients who experience these side effects should seek immediate medical attention. Interactions Proleukin may interact with other medications, particularly those that affect the immune system. Patients should inform their healthcare provider of all medications and supplements they are taking before starting Proleukin. This medication should not be used in combination with other immunosuppressant drugs, as this can increase the risk of infection. Generic Options There is currently no generic version of Proleukin on the market. This medication is only available as a brand-name drug, and it can be quite expensive. Patients who require Proleukin may be eligible for financial assistance programs to help cover the cost of the medication. Conclusion Proleukin is a valuable medication in the treatment of metastatic melanoma and metastatic renal cell carcinoma. This medication works by stimulating the immune system to attack cancer cells, which can help to slow the progression of the disease. While Proleukin is generally well-tolerated, it can cause side effects, particularly in patients with underlying health conditions. Patients should discuss the risks and benefits of Proleukin with their healthcare provider to determine if this medication is right for them.