Kineret: Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Kineret is a brand name for the medication anakinra, a biological response modifier that is used primarily in the treatment of rheumatoid arthritis. Here is an overview of Kineret, including its uses, dosage, demographic, side effects, interactions, and generic options. Uses Kineret is used to treat rheumatoid arthritis, a chronic inflammatory disorder that affects the joints, as well as juvenile idiopathic arthritis, a similar condition that affects children. It works by blocking the action of a protein called interleukin-1, which plays a key role in the inflammation associated with these conditions. By inhibiting the production of this protein, Kineret reduces inflammation and swelling in the joints, leading to a decrease in the associated pain and stiffness. Dosage Kineret is available as a subcutaneous injection, which is administered under the skin. The recommended dosage is 100mg/day, given once daily. The injection should be given at the same time every day, and the site of injection should be rotated to avoid skin irritation. Demographic Kineret is approved for use in adults with rheumatoid arthritis and children with juvenile idiopathic arthritis. It is typically used in individuals who have not responded to other treatments for these conditions, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologic agents. Kineret is not recommended for individuals with a known allergy to anakinra or any of its components. Side Effects Common side effects of Kineret include redness, itching, swelling, and pain at the injection site. These side effects are typically mild and go away on their own within a few days. Other possible side effects of Kineret include headaches, nausea, diarrhea, and throat irritation. In rare cases, individuals taking Kineret may experience more serious side effects, such as infections or allergic reactions. If you experience any unusual symptoms while taking Kineret, contact your doctor immediately. Interactions Kineret may interact with other medications that affect the immune system, including corticosteroids and immunosuppressants. It is important to tell your doctor about all the medications you are currently taking before starting Kineret. In addition, Kineret should not be used with live vaccines, as it may interfere with the effectiveness of the vaccine. Generic Options Anakinra, the active ingredient in Kineret, is available in generic form under the name anakinra. Generic anakinra may be less expensive than brand-name Kineret, although it is important to consult with your doctor before switching to a generic version of the medication. Conclusion Kineret (anakinra) is a biological response modifier that is used primarily in the treatment of rheumatoid arthritis and juvenile idiopathic arthritis. It works by blocking the action of a protein called interleukin-1, which plays a key role in the inflammation associated with these conditions. Kineret is available as a subcutaneous injection and is typically given once daily. Common side effects of Kineret include redness, itching, swelling, and pain at the injection site, while more serious side effects are rare. Kineret may interact with other medications that affect the immune system and should not be used with live vaccines. Anakinra, the active ingredient in Kineret, is available in generic form.