KEDRAB: An Overview of Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Rabies is a viral disease that affects mammals, including humans. Once the signs of rabies appear, it becomes almost impossible to treat. Therefore, vaccination is crucial in preventing the disease. If someone is exposed to rabies, they should receive post-exposure prophylaxis (PEP) immediately. A new drug called KEDRAB has been developed for the treatment of rabies. In this article, we will discuss the uses, dosage, demographic, side effects, interactions, and generic options of KEDRAB. What is KEDRAB? KEDRAB is a purified, sterile, human rabies immunoglobulin (HRIG) indicated for passive, transient post-exposure prophylaxis (PEP) of rabies infection in patients of all ages (including neonates, infants, children, adolescents, adults, and elderly people) who have been exposed to the virus. How does KEDRAB work? KEDRAB works by neutralizing the rabies virus. It contains antibodies that bind to the virus, making it harmless. These antibodies come from human plasma and are purified to remove any potential viral pathogens that could cause infections in the recipient. What are the uses of KEDRAB? KEDRAB is used as a part of the post-exposure prophylaxis (PEP) regimen after exposure to rabies. It is recommended for use along with the rabies vaccine. KEDRAB helps to provide immediate protection against the virus, while the vaccine works to generate an active immune response for long-term protection. What is the dosage of KEDRAB? The dosage of KEDRAB varies according to the patient's weight and the extent of exposure to the rabies virus. The recommended dosage is 20 IU/kg body weight. The maximum dosage should not exceed 40 IU/kg. Who is the demographic of KEDRAB? KEDRAB can be used for treating rabies in patients of all ages, including neonates, infants, children, adolescents, adults, and elderly people. What are the side effects of KEDRAB? Like all medications, KEDRAB can cause side effects. The most common side effects of KEDRAB include headache, gastrointestinal symptoms, pain, and swelling at the injection site, low fever, allergic reaction, and nausea. These side effects usually resolve on their own within a few days. What are the interactions of KEDRAB? KEDRAB should not be administered simultaneously with the rabies vaccine. It should be administered at a separate site from the vaccine. Other medications that may interact with KEDRAB include immunosuppressive drugs and live vaccines. What are the generic options of KEDRAB? KEDRAB is currently the only HRIG available in the United States. However, several generic HRIGs are available in other countries. These generic options include Imorab, Hyperab, and Sagirab. Conclusion In conclusion, KEDRAB is a purified, sterile, human rabies immunoglobulin (HRIG) used for passive, transient post-exposure prophylaxis (PEP) of rabies infection in patients of all ages who have been exposed to the virus. The recommended dosage varies according to the patient's weight and the extent of exposure to the rabies virus. Although KEDRAB has some potential side effects and drug interactions, it is considered safe and effective for treating rabies.