Iressa: A Comprehensive Guide on Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Iressa, also known as Gefitinib, is a medication used in the treatment of patients suffering from non-small cell lung cancer. It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs) that work by blocking signals that cause the growth and spread of cancer cells. In this article, we will cover a detailed guide on the usage, dosage, demographic, side effects, interactions, and generic options associated with Iressa. Uses of Iressa: Iressa is prescribed for the treatment of advanced or metastatic non-small cell lung cancer (NSCLC) in patients who have experienced failure of both cytotoxic chemotherapy and platinum-based therapy. It is not recommended for use in patients with squamous cell lung cancer. Dosage of Iressa: The recommended dose of Iressa is 250 mg orally once daily, with or without food. The tablets should be swallowed whole with water. The medication should be taken at the same time each day to ensure that the drug levels in the body remain consistent. The dosage may be adjusted based on individual patient needs, depending on their response to treatment and the occurrence of side effects. Demographic of Iressa: Iressa is approved for use in adults (18 years or older) with non-small cell lung cancer. The drug has not been studied in pediatric patients, and its safety and efficacy have not been established in this population. Additionally, Iressa should be used with caution in elderly patients and patients with liver or kidney impairment. Side Effects of Iressa: Iressa may cause side effects like any other medication. Common side effects include diarrhea, skin rash or itching, acne, nausea, vomiting, loss of appetite, and dry skin. Other side effects may include changes in skin color, hair loss or thinning, fatigue, headache, and nosebleeds. Serious side effects of Iressa include interstitial lung disease (ILD), which is a potentially life-threatening lung disease that can cause symptoms like shortness of breath, coughing, and fever. Other serious side effects may include liver problems, kidney problems, and gastrointestinal perforations. Interactions of Iressa: Iressa may interact with other medications, leading to adverse events. Patients should inform their doctor of all the medication they are currently taking, including prescription, non-prescription, and herbal products. Iressa is metabolized by CYP3A4 and CYP2D6 enzymes, and as such, should not be administered concurrently with medications that affect these enzymes like clarithromycin, cyclosporine, ketoconazole, and ritonavir. Generic Options of Iressa: Iressa is a brand name for Gefitinib, and several generic versions of the medication are available under different brand names like Geffy, Zefea, Geftinat, Efumora, and Iressa I. These generic versions are just as effective as the brand-name drug and may be less expensive. Conclusion: Iressa is a tyrosine kinase inhibitor medication used in the treatment of non-small cell lung cancer. The recommended dosage is 250mg taken orally once daily. Patients should be aware of potential side effects, interactions, and precautions associated with Iressa use. Generic versions of Iressa, which are just as effective as the brand-name drug, are available under different brand names. If you have further questions regarding the use, dosage, demographic, side effects, interactions, and generic options associated with Iressa, consult with your healthcare provider. Citation: FDA Drugs, 2015, “Iressa (gefitinib) Tablet” https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206995s005lbl.pdf