Invega Sustenna: A Comprehensive Guide Invega Sustenna, also known as paliperidone palmitate, is an antipsychotic medication used to treat schizophrenia in adults. It is administered through intramuscular injection once a month. In this article, we will explore the uses, dosage, demographic, side effects, interactions, and generic options of Invega Sustenna. Uses Invega Sustenna is commonly prescribed to manage symptoms of schizophrenia. It works by blocking the activity of certain chemicals in the brain that are associated with psychosis, including dopamine and serotonin. Invega Sustenna can help to control hallucinations, delusions, and other symptoms associated with schizophrenia. Dosage The recommended starting dose of Invega Sustenna is 234 mg, administered once per month. The dose can be adjusted based on individual patient needs. The maximum dose for Invega Sustenna is 819 mg per month. Doses greater than 234 mg should be given as two injections at separate sites. Demographic Invega Sustenna is approved for use in adults aged 18 to 65 years old. It has not been studied in pediatric patients or in patients over the age of 65. Invega Sustenna is metabolized by the liver, so patients with liver impairment may require a lower dose of the medication. Side Effects As with any medication, Invega Sustenna may cause side effects. Some of the common side effects of Invega Sustenna include: - Dizziness - Headache - Drowsiness - Akathisia (restlessness) - Tremors - Injection site reactions such as pain, redness, or swelling - Weight gain - Elevated prolactin levels - Changes in blood pressure In rare cases, Invega Sustenna may cause more serious side effects such as: - Neuroleptic malignant syndrome (a rare but potentially life-threatening condition characterized by muscle rigidity, fever, and autonomic instability) - Tardive dyskinesia (a movement disorder characterized by involuntary movements of the face and body) - Hyperglycemia (high blood sugar) - Dystonia (involuntary muscle contractions) - Seizures Interactions Invega Sustenna may interact with other medications. Patients who are taking Invega Sustenna should inform their healthcare provider of any other medications they are taking, including over-the-counter medications and supplements. Invega Sustenna may interact with medications that lower the seizure threshold, such as antidepressants, antihistamines, and antipsychotics. Generic options Invega Sustenna is the brand name for paliperidone palmitate. There are currently no generic versions of Invega Sustenna available. However, generic versions of paliperidone extended-release tablets, an oral form of paliperidone, are available. Patients who are unable to afford the brand name version of Invega Sustenna may be able to switch to the generic oral form of paliperidone. Conclusion Invega Sustenna is a medication used to manage symptoms of schizophrenia in adults. It is administered through intramuscular injection once a month. Patients taking Invega Sustenna may experience side effects, and it may interact with other medications. Patients who cannot afford the brand name version of Invega Sustenna may be able to switch to the generic oral form of paliperidone. If you are experiencing symptoms of schizophrenia, speak with your healthcare provider to determine if Invega Sustenna is right for you.