Indocin SR: A Comprehensive Guide to its Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Indocin SR, generically known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) used to alleviate pain and reduce inflammation caused by different types of arthritis, gout attacks, and other medical conditions. Here’s everything you need to know about Indocin SR, including its uses, dosage, demographic, side effects, interactions, and generic options. Uses Indocin SR is primarily used to manage the following medical conditions that cause pain and inflammation: 1. Arthritis - this includes osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other types of arthritis 2. Gout attacks - Indocin SR is prescribed to relieve pain and inflammation caused by gout attacks, as well as to prevent future attacks 3. Bursitis and tendonitis - these conditions can cause pain and swelling in the joints and muscles that can be managed by Indocin SR 4. Headaches - Indocin SR can be used to relieve moderate to severe migraine headaches Dosage Indocin SR is available in capsule form for oral administration. The dosage for Indocin SR varies depending on the medical condition and the age, weight, and tolerance of the patient. For adults, the initial recommended dose of Indocin SR is 75 mg to 150 mg daily, divided into 2 to 3 doses. The maximum daily dose is 200 mg. For children, the dosage is based on their weight, with a maximum dosage of 4 mg/kg/day or 150 mg/day, whichever is less. It’s important to take Indocin SR with food or milk to avoid stomach upset. Demographic Indocin SR can be prescribed to adults and children aged 14 years and above. However, it’s not safe to administer Indocin SR to children younger than 14 years, pregnant women, breastfeeding mothers, or people who are allergic to NSAIDs. Indocin SR should also be used with caution in people living with liver diseases, kidney diseases, heart diseases, high blood pressure, asthma, or a history of stomach ulcers. Side effects Common side effects of Indocin SR include: 1. Stomach upset 2. Diarrhea 3. Nausea 4. Abdominal pain 5. Headache 6. Dizziness 7. Ringing in the ears 8. Increased blood pressure 9. Difficulty sleeping 10. Swelling of the feet and hands Indocin SR can also cause severe side effects, such as: 1. Allergic reactions - symptoms include difficulty breathing, skin rash, hives, itching, and swelling of the face, throat, tongue, or lips 2. Stomach bleeding - this can be identified by stomach pain, black or tarry stools, blood in vomit, and vomiting blood 3. Kidney problems - symptoms include decreased urine production, dark urine, and swelling of the feet and ankles 4. Liver problems - symptoms include yellowing of the skin or eyes, dark urine, and upper abdominal pain 5. Heart attack or stroke - symptoms include chest pain, shortness of breath, weakness, confusion, and speech difficulty Interactions Indocin SR can interact with other medications, supplements, and herbs and cause severe side effects or reduce the effectiveness of the medication. Here are some of the drugs that can interact with Indocin SR: 1. Blood thinners, such as warfarin, aspirin, and clopidogrel 2. Corticosteroids, such as prednisone 3. ACE inhibitors, such as lisinopril and enalapril 4. Diuretics, such as furosemide and hydrochlorothiazide 5. Lithium 6. Methotrexate 7. Digoxin 8. Probenecid 9. Antidepressants, such as sertraline and fluoxetine Consult your healthcare provider before using Indocin SR if you’re taking any of the medications mentioned above or any other drug. Generic Options Indocin SR is a brand-name drug that has a generic version called indomethacin. The generic version is usually cheaper than the brand-name drug and has the same active ingredients and effectiveness. Other generic variations of Indocin SR include: 1. Indocap SR 2. Indocid SR 3. Indonaprox SR 4. Indosurta-25 SR Conclusion Indocin SR is a potent NSAID that’s used to alleviate pain and reduce inflammation caused by different types of arthritis, gout attacks, and other medical conditions. Before taking Indocin SR, consult your healthcare provider to determine the appropriate dosage, monitor any side effects, and inform you of any necessary precautions. Remember to store Indocin SR at room temperature away from children, pets, and moisture.