Ibrance: Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Ibrance, also known as Palbociclib, is a prescription medication used to treat certain types of breast cancer. It belongs to a class of drugs called cyclin-dependent kinase (CDK) inhibitors. In this article, we will provide an SEO optimized medically cited article on Ibrance covering its uses, dosage, demographic, side effects, interactions, and generic options. Uses: Ibrance is used in combination with letrozole to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in postmenopausal women. It is also used in combination with fulvestrant to treat HR+/HER2- metastatic breast cancer in women whose disease has progressed after they have taken other hormone therapy. Ibrance works by blocking certain proteins called CDK4 and CDK6 that promote the growth of cancer cells. Blocking these proteins slows down the growth and spread of cancer cells. Dosage: The dosage of Ibrance depends on the patient's weight and the drugs they are taken with. The recommended dose is 125 mg, which should be taken orally once a day for 21 consecutive days, followed by a 7-day break period. The medication should be taken with food at roughly the same time each day. If a dose is missed, the patient should take it as soon as they remember. If the missed dose is remembered the next day, the patient should skip the missed dose and resume their normal schedule. Demographic: Ibrance is approved for use in postmenopausal women with HR+/HER2- metastatic breast cancer who have not yet received hormone therapy or whose disease has progressed after taking other hormone therapy. Additionally, it is prescribed for women whose tumors have grown despite antiestrogen therapy. Ibrance is not approved for use in men or children. Side Effects: Ibrance is generally well-tolerated by patients. However, some side effects may occur and should be reported to a doctor. Common side effects may include: - Nausea - Vomiting - Diarrhea - Constipation - Tiredness/Fatigue - Hair Loss - Mouth Sores - Loss of Appetite - Infections - Low White Blood Cell Count - Low Red Blood Cell Count - Low Platelet Count - Headache - Difficulty Falling or Staying Asleep Serious side effects may include: - Severe Infection - Low Blood Cell Counts - Pulmonary Embolism - Gastrointestinal Perforation Interactions: Ibrance may interact with other medications the patient is taking. Patients should tell their doctor about all the drugs they are taking, including prescription, over-the-counter, and herbal products. This includes blood thinners, cholesterol-lowering medications, and contraceptives. Generic Options: Ibrance is a brand-name medication and does not have a generic equivalent. However, the active ingredient in Ibrance is palbociclib. Palbociclib is available as a generic medication under the name Palbace 100 mg Capsule. Conclusion: Ibrance is a prescription medication used for the treatment of HR+/HER2- metastatic breast cancer in postmenopausal women. It blocks certain proteins that promote the growth of cancer cells, slowing down their growth and spread. The patient's dosage depends on their weight and other medications they are taking. Ibrance is generally well-tolerated, but some side effects may occur. Patients should talk to their doctor about any potential interactions with other medications they are taking. Finally, Ibrance is a brand-name medication that does not have a generic equivalent, but the active ingredient in Ibrance is available as a generic medication under the name Palbace 100 mg Capsule.