Herceptin: Uses, Dosage, Demographics, Side Effects, Interactions & Generic Options Herceptin (Trastuzumab) is a medication that is primarily used in the treatment of breast cancer. It is a type of targeted therapy that works by attaching to the HER2 protein in cancer cells, thereby inhibiting the growth and division of these cells. Trastuzumab is usually administered along with chemotherapy or radiation therapy. Uses Herceptin is primarily used in the treatment of breast cancer. It is used to treat HER2-positive breast cancer, which is a subtype of breast cancer that has higher levels of the HER2 protein. This protein is known to play a crucial role in the growth and division of breast cancer cells. Herceptin works by attaching to the HER2 protein, thereby inhibiting the growth and division of breast cancer cells. Dosage The dosage of Herceptin depends on the individual's weight and the stage of the breast cancer. It is usually administered through intravenous infusion. The first dose is usually larger and followed by smaller doses once a week or once every three weeks. The treatment duration may vary from a few weeks to more than a year, depending on the individual's response. Demographics Herceptin is primarily used in the treatment of HER2-positive breast cancer. HER2-positive breast cancer is more commonly found in women than in men. According to the American Cancer Society, about 15-20% of breast cancer cases are HER2-positive. Side Effects Like any medication, Herceptin has potential side effects. Some of the common side effects of Herceptin include: - Fatigue - Fever - Nausea - Diarrhea - Headache - Infections - Muscle and joint pain - Insomnia - Allergic reactions In rare cases, Herceptin can cause serious side effects, such as: - Heart problems - Lung problems - Infusion reactions - Reduced blood count Interactions Herceptin may interact with other medications, including other chemotherapy drugs and antibiotics. It is essential to inform your doctor about all the medications you are taking before starting Herceptin treatment. Generic Options Herceptin is a brand name medication, and there is no generic version available in the United States. However, biosimilars, which are similar to the original medication but not identical, are available. Biosimilars are approved by the FDA for use in the treatment of HER2-positive breast cancer. Conclusion Herceptin (Trastuzumab) is a targeted therapy medication used in the treatment of HER2-positive breast cancer. It works by inhibiting the growth and division of cancer cells by attaching to the HER2 protein. Herceptin is usually administered along with chemotherapy or radiation therapy through intravenous infusion. The dosage, side effects, and interactions of Herceptin should be discussed with your healthcare provider before starting the treatment. Although there is no generic version of Herceptin available, biosimilars have been approved for use by the FDA.