Haegarda: What You Need to Know Haegarda is a prescription medicine that is used to prevent hereditary angioedema (HAE) attacks in adults and adolescents over 12 years of age. HAE is a rare genetic disorder that can cause severe swelling in various parts of the body, including the face, throat, and limbs. Haegarda is a subcutaneous injection that can be taken every 3 to 4 days. Uses of Haegarda Haegarda is used to prevent attacks of HAE in adults and adolescents over 12 years of age. HAE is caused by a deficiency of a protein called C1 esterase inhibitor (C1-INH), which helps regulate inflammation in the body. Haegarda contains a human plasma-derived C1 esterase inhibitor and can help replenish the missing protein in patients with HAE. Dosage of Haegarda The recommended dose of Haegarda is based on the patient's body weight and ranges from 10 to 60 units per kilogram of body weight. The injection should be administered subcutaneously in the abdomen, thigh, or upper arm every 3 to 4 days. Patients should receive initial training from a healthcare professional on how to prepare and administer the injection. Demographic for Haegarda Haegarda is approved for use in adults and adolescents over 12 years of age with HAE. It is not recommended for use in children under 12 years of age or in patients with a history of severe allergic reactions to C1-INH products. Side Effects of Haegarda The most common side effects of Haegarda include injection site reactions, such as redness, swelling, or itching. Some patients may also experience headache, nausea, diarrhea, or rash. Rarely, patients may develop an allergic reaction to Haegarda, which can cause difficulty breathing, chest pain, or swelling of the face or tongue. Patients should contact their healthcare provider immediately if they experience any of these symptoms. Interactions with Haegarda There are no known drug interactions with Haegarda. Patients should inform their healthcare provider about all medications they are taking, including prescription and over-the-counter drugs, herbal supplements, and vitamins. Generic Options for Haegarda There are currently no generic versions of Haegarda available. However, there are other C1-INH products on the market, such as Berinert and Cinryze, that can also be used to treat HAE. In conclusion, Haegarda is a prescription medicine used to prevent HAE attacks in adults and adolescents over the age of 12. It contains a human plasma-derived C1 esterase inhibitor and is administered subcutaneously every 3 to 4 days. Patients should receive initial training from a healthcare professional on how to prepare and administer the injection. The most common side effects of Haegarda include injection site reactions, headache, nausea, and rash. Patients should contact their healthcare provider immediately if they experience difficulty breathing, chest pain, or swelling of the face or tongue. There are no known drug interactions with Haegarda, and there are other C1-INH products available on the market.