Fetzima: A Comprehensive Guide on Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Fetzima (levomilnacipran) is a prescription medication classified as a serotonin-norepinephrine reuptake inhibitor (SNRI). It is primarily used for the treatment of major depressive disorder (MDD) in adults. This article will provide an overview of Fetzima's uses, dosage, demographic, side effects, interactions, and generic options. Fetzima's Uses Fetzima is approved by the Food and Drug Administration (FDA) for the treatment of MDD in adults. MDD is a mental health disorder that causes persistent feelings of sadness and loss of interest in regularly enjoyable activities. Fetzima works by increasing the levels of neurotransmitters in the brain such as norepinephrine and serotonin, which regulate mood, appetite, and sleep. Dosage Fetzima is available in 20 mg, 40 mg, 80 mg, and 120 mg capsules. The recommended starting dose for Fetzima is 20 mg orally taken once daily with or without food. The dosage may be increased by 20 mg increments every two to seven days based on the patient's response and tolerability. The maximum dose limit is 120 mg daily. A gradual titration rate is necessary to avoid withdrawal symptoms and potential adverse effects. Demographic Fetzima is approved for use in adults aged 18 years and older with MDD. The medication may not be suitable for everyone, especially those with a history of cardiovascular disease, seizures, or liver disease. Pregnant and breastfeeding women should also avoid Fetzima as it can harm the fetus and pass into breast milk. Side Effects Like all medications, Fetzima may cause side effects, ranging from mild to severe. Some common side effects include: - Nausea, vomiting, and diarrhea - Insomnia - Dry mouth - Dizziness or lightheadedness - Sweating - Fatigue or tiredness - Decreased appetite - Constipation In rare cases, Fetzima may cause more severe side effects such as elevated blood pressure, mania, seizures, and serotonin syndrome. It is essential to contact a healthcare provider immediately if experiencing any unusual symptoms. Interactions Fetzima may interact with other medications, supplements, and substances. It is essential to inform the healthcare provider about any prescription or non-prescription medications, herbal products, and dietary supplements currently being taken before starting Fetzima. Some substances that may interact with Fetzima include: - Monoamine oxidase inhibitors (MAOIs) - Other SNRIs or selective serotonin reuptake inhibitors (SSRIs) - St. John's Wort - Triptans used to treat migraines - Certain antibiotics such as linezolid and isoniazid Generic Options Fetzima's generic equivalent, levomilnacipran, is available but may not be offered by all pharmacies. Generic options may differ in inactive ingredients, shape, and color from the brand-name medication, but they contain the same active ingredient and are considered equally effective and safe. Conclusion Fetzima (levomilnacipran) is a prescription medication used for the treatment of major depressive disorder in adults. It works by increasing the levels of neurotransmitters in the brain that regulate mood, appetite, and sleep. Fetzima is available in four different doses, and a gradual titration rate is necessary to avoid withdrawal symptoms and potential adverse effects. Common side effects include nausea, vomiting, insomnia, and dizziness, while severe side effects are rare. Fetzima may interact with other medications, supplements, and substances, and generic equivalents are available. Consult a healthcare provider for any questions or concerns regarding Fetzima's use.