Doribax (also known as doripenem) is an antibiotic medication used in the treatment of serious bacterial infections such as pneumonia, urinary tract infections, and intra-abdominal infections. It is a member of the carbapenem class of antibiotics, which are considered broad-spectrum and highly effective in combating bacterial infections. Uses Doribax is approved by the Food and Drug Administration (FDA) for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and for the treatment of patients with pneumonia. It is also used in the treatment of infections caused by multi-drug-resistant bacteria. Dosage The recommended dose of Doribax for the treatment of complicated intra-abdominal infections and complicated urinary tract infections is 500 mg administered intravenously (IV) every 8 hours over 1-hour infusion. For the treatment of pneumonia, the recommended dose is 1 gram administered IV every 8 hours over a 4-hour infusion. The dosage may be adjusted based on the severity of the infection, the age, and weight of the patient, and the patient's renal function. Demographic Doribax can be used in both adult and pediatric populations. It is generally not recommended for patients with a known hypersensitivity to doripenem or other beta-lactam antibiotics. Side Effects The most common side effects of Doribax include nausea, diarrhea, headache, and fever. Other possible side effects may include abdominal pain, urinary tract infections, and skin rashes. If a patient experiences any serious side effects such as allergic reactions including hives or anaphylaxis, seizures, or signs of kidney damage such as changes in urine output, they should immediately seek medical attention. Interactions Doribax may interact with other medications including probenecid and valproic acid. It is important to inform the healthcare provider of all current medications, including over-the-counter medications, herbal supplements, and vitamins, to avoid potential interactions. Generic Options Doripenem is the generic name for Doribax. There are no other generic options currently available in the United States. In conclusion, Doribax is a potent antibiotic medication used to treat serious bacterial infections. The recommended dosage and administration must be strictly followed to minimize the potential for adverse reactions or resistance. Patients must communicate with their healthcare provider to identify any potential interaction with other medications as well as any existing medical conditions and history of hypersensitivity prior to administration. Doribax is a promising option to mitigate the growing number of multi-drug-resistant bacterial infections, underscoring the importance of the healthcare provider's role in the prescription, administration, and management of treatments.