Dibenzyline: Uses, Dosage, Demographic, Side Effects, Interactions and Generic Options Dibenzyline (phenoxybenzamine hydrochloride) is a drug used to treat high blood pressure and certain medical conditions such as pheochromocytoma, a tumor that produces excessive amounts of adrenaline. In this medically cited article, we will discuss the following aspects of Dibenzyline: 1. Uses 2. Dosage 3. Demographic 4. Side Effects 5. Interactions 6. Generic Options 1. Uses Dibenzyline is primarily used to treat high blood pressure (hypertension) caused by an overactive adrenal gland. It works by blocking the action of a chemical called adrenaline, which is released by the adrenal gland and causes blood vessels to narrow. It is also used to treat pheochromocytoma, a rare adrenal tumor that can cause high blood pressure and other symptoms such as headaches, anxiety, sweating, and palpitations. Dibenzyline helps to control these symptoms by reducing the production of adrenaline. 2. Dosage The dosage of Dibenzyline varies depending on the condition being treated. The usual adult dose for high blood pressure is 10 mg to 20 mg taken 2 to 3 times a day. The maximum daily dose is 120 mg. For pheochromocytoma, the initial dose is usually 10 mg twice daily, with the dose gradually increased as needed. The maximum daily dose is 640 mg. The dose for children is based on their weight and is usually 0.2 mg per kilogram of body weight, up to a maximum of 10 mg per dose. Dibenzyline is available in tablet form and should be taken with food to reduce stomach upset. 3. Demographic Dibenzyline is indicated for use in adults and children over the age of 12. It should not be used during pregnancy or breastfeeding as it may harm the fetus or infant. It should also be used with caution in elderly patients as they may be more susceptible to side effects. 4. Side Effects Dibenzyline can cause a range of side effects, including: - Dizziness - Fatigue - Nausea - Vomiting - Dry mouth - Constipation - Headache - Blurred vision - Sweating - Sexual dysfunction More severe side effects may include: - Hypertensive crisis (extremely high blood pressure) - Heart palpitations - Chest pain - Shortness of breath - Fainting If you experience any of these symptoms, you should seek medical attention immediately. In rare cases, Dibenzyline may also cause an allergic reaction, which can cause hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. 5. Interactions Dibenzyline may interact with other medications, including other blood pressure medications, antidepressants, and medications used to treat migraines. It may also interact with alcohol, causing dizziness or fainting. You should inform your doctor of all medications you are taking, including vitamins and herbal supplements, before starting treatment with Dibenzyline. 6. Generic Options Dibenzyline is only available as a brand-name medication. However, there are other medications that work in a similar way to Dibenzyline that are available as generic options, including phentolamine and doxazosin. In conclusion, Dibenzyline is a medication used to treat high blood pressure and pheochromocytoma. It works by blocking the action of adrenaline, which can cause blood vessels to narrow. Although it can be effective in treating these conditions, it can also cause a range of side effects, and may interact with other medications. Patients should inform their doctor of all medications they are taking and report any side effects to their healthcare provider.