Depakote ER: Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Depakote ER (divalproex sodium) is a prescription medication that is used to treat certain types of seizures, and to manage the manic phase of bipolar disorder. It works by increasing the levels of the neurotransmitter GABA in the brain, which helps to reduce the frequency and severity of seizures and manic episodes. Below is a comprehensive guide to Depakote ER, including its uses, dosage, demographic, side effects, interactions, and generic options. Uses Depakote ER is primarily used to treat seizures that are caused by epilepsy and focal seizures. It is also used to manage the manic phase of bipolar disorder. Depakote ER effectively controls seizures when used in combination with other antiepileptic drugs, but it is less effective when used alone. The drug cannot cure seizures or bipolar disorder, but it helps to control symptoms and prevent recurrences. Dosage Depakote ER is available in tablets of 250 mg and 500 mg. The recommended dosage for adults and children over 10 years old is 25 mg/kg/day. Dosage may vary depending on the patient's age, weight, and general health condition. Patients should take the tablets with food to avoid stomach upset. Demographic Depakote ER is a medication that is primarily used by adults and children over 10 years old. The drug may be prescribed to pregnant women who suffer from epilepsy or bipolar disorder, but the drug is not recommended for use by breastfeeding mothers. Depakote ER is not recommended for use in children under the age of two. Side Effects Depakote ER may cause a range of side effects, including: - Nausea and vomiting - Dizziness - Fatigue - Tremors - Hair loss - Weight gain - Diarrhea - Blurred vision - Headaches - Increased appetite - Insomnia Depakote ER may also cause more serious side effects, such as liver damage, pancreatitis, and blood disorders. People who experience any adverse effects should immediately contact their doctor. Interactions Depakote ER may interact with a range of other medications. Patients should inform their doctor of all medications, including prescription, over-the-counter, and herbal supplements they are taking. Depakote ER may interact adversely with: - Aspirin - Blood thinners - Carbapenems - Erythromycin - felbamate - Lamotrigine - Phenytoin - Topiramate - Ziprasidone Generic Options Depakote ER is a brand name medication and is therefore more expensive than its generic equivalents, divalproex sodium ER and valproic acid ER. These are equally effective and may be preferred by patients who wish to save on medication expenses. Conclusion Depakote ER is a medication that is commonly used to treat seizures and manage bipolar disorder. Patients should always follow the dosage recommendations of their doctor and inform their physician of all side effects or adverse interactions with other medications. Depakote ER has a range of side effects, both mild and severe, and caution should be exercised when taking the drug. Patients may choose to use generic alternatives which are equally effective, but less expensive.