Cotellic
PHONETIC PRONUNCIATION: Cotellic
Description
Cotellic (cobimetinib) is a prescription medication used in combination with Zelboraf (vemurafenib) to treat unresectable or metastatic melanoma with a BRAF V600E or V600K mutation. This medication belongs to a class of drugs known as protein kinase inhibitors and works by blocking the growth and spread of cancer cells. Here's everything you need to know about Cotellic including its uses, dosage, demographic, side effects, interactions, and generic options. Uses Cotellic is prescribed to treat a specific type of skin cancer called melanoma that has spread to other parts of the body. It is used in combination with another medication called Zelboraf to treat people who have a specific type of BRAF gene mutation. This type of mutation is found in about half of all melanoma cases, and it causes cells to divide and grow uncontrollably. Cotellic helps to slow down or stop the growth of cancer cells, thereby increasing the chances of survival. Dosage Cotellic is available in the form of tablets that are taken orally. The recommended dose for Cotellic is 60 mg once daily for 21 days followed by a 7-day break. It is usually taken in combination with Zelboraf. Your doctor will determine the right dosage for you based on your medical history and other factors such as your age, weight, and health condition. Demographic Cotellic is primarily used to treat patients with a specific type of skin cancer called melanoma. It is prescribed to adults aged 18 years and above who have been diagnosed with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation. Cotellic is not recommended for use in children since its effectiveness and safety have not been established in this population. Side Effects Like all medications, Cotellic may cause side effects. Common side effects of Cotellic include diarrhea, nausea, vomiting, stomach pain, loss of appetite, fever, fatigue, headache, joint pain, and muscle pain. These side effects are usually mild and do not require medical attention. However, if they persist or become severe, you should contact your doctor immediately. Less common but more serious side effects include rash, hives, itching, difficulty breathing, swelling of the face, lips, tongue, or throat, and liver problems. These symptoms can be signs of an allergic reaction or other serious health condition. If you experience any of these symptoms, seek medical attention immediately. Interactions Cotellic can interact with other medications, herbs, and supplements you may be taking. Therefore, it is important to inform your doctor of all drugs you are taking, including prescription, over-the-counter, and herbal products. Cotellic should not be taken in combination with strong CYP3A4 inhibitors, as this can increase the risk of adverse events. Generic Options Cotellic is currently available only in branded form. There is no generic alternative available at this time. In conclusion, Cotellic is a medication used to treat a specific type of skin cancer called melanoma that has spread to other parts of the body. It is prescribed in combination with another medication called Zelboraf to treat patients with a BRAF V600E or V600K mutation. While it may cause side effects, they are usually mild and do not require medical attention. If you suspect any serious side effects, contact your doctor immediately. Additionally, it is important to inform your doctor of all medications you are taking, including prescription, over-the-counter, and herbal products, as they may interact with Cotellic.
Faq for Cotellic
Cotellic (cobimetinib) is used in combination with another drug called Zelboraf (vemurafenib) to treat a specific type of skin cancer called melanoma that has metastasized or cannot be removed by surgery.
Cotellic is a MEK inhibitor, which means it works by blocking a protein called MEK that is involved in the growth and spread of cancer cells. By inhibiting MEK, Cotellic helps prevent the growth and spread of melanoma cells.
The recommended dosage of Cotellic is 60 mg taken orally once daily for the first 21 days of each 28-day cycle. It is usually used in combination with Zelboraf, and both drugs should be taken at the same time each day.
Common side effects of Cotellic include diarrhea, nausea, vomiting, rash, increased sensitivity to sunlight, fever, hair loss, joint pain, fatigue, and headache. It is important to inform your doctor about any side effects experienced.
Treatment with Cotellic is usually given in cycles of 28 days, with 21 days of taking the drug followed by a 7-day break. The treatment may continue as long as it is effective and tolerated by the patient.
Yes, there are several precautions and warnings associated with Cotellic. These include the risk of severe bleeding, heart problems, liver toxicity, eye problems, and the risk of severe skin reactions. It is important to discuss any pre-existing conditions or medications with your doctor before starting Cotellic.
No, Cotellic should not be taken during pregnancy or while breastfeeding. It can cause harm to the unborn baby and may pass into breast milk. It is important to use effective contraception during treatment and discuss the risks with your doctor.
The safety and effectiveness of Cotellic have not been established in children, so it is generally not recommended for use in pediatric patients. The use of Cotellic in children should be discussed with a pediatric oncologist.