Calquence
PHONETIC PRONUNCIATION: Calquence
Description
Calquence: A Breakthrough Treatment for Chronic Lymphocytic Leukemia Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. It is the most common form of leukemia in adults in Western countries. The good news is that there have been significant advances in the treatment of CLL over the past decade, including the development of targeted therapies like Calquence. Calquence, also known as acalabrutinib, is an FDA-approved oral medication used to treat adults with CLL or small lymphocytic lymphoma (SLL). It falls under a class of drugs called Bruton's tyrosine kinase (BTK) inhibitors, which work by blocking the BTK protein in cancer cells, preventing their growth and survival. Uses Calquence is used to treat adults with CLL or SLL who have received at least one prior therapy. It is also approved for use as a first-line treatment for CLL in combination with obinutuzumab, an immunotherapy drug. Dosage The recommended dose of Calquence is 100 mg taken orally twice daily. It should be swallowed whole with water and can be taken with or without food. The dosage may need to be adjusted based on factors such as age, weight, and kidney function. Demographic Calquence is approved for use in adults with CLL or SLL who have received at least one prior therapy. It is not recommended for use in children or pregnant women. Side Effects Like all medications, Calquence can cause side effects. Some common side effects include headache, diarrhea, fatigue, nausea, and upper respiratory tract infection. These side effects are usually mild and go away on their own. However, Calquence can cause more serious side effects, including bleeding, infections, and rare cases of atrial fibrillation (a type of irregular heart rhythm). Patients should contact their healthcare provider immediately if they experience any of these symptoms. Interactions Calquence can interact with other medications, including strong CYP3A inhibitors and inducers. Patients should inform their healthcare provider of all medications they are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Generic Options Currently, there is no generic version of Calquence available on the market. Conclusion Calquence is a targeted therapy that has been shown to be effective in the treatment of CLL and SLL. Although it can cause side effects, most are mild and go away on their own. Patients should be aware of the potential risks and benefits of taking Calquence and speak with their healthcare provider if they have any questions or concerns.
Faq for Calquence
Calquence (acalabrutinib) is a medication used for the treatment of certain types of cancers, specifically mantle cell lymphoma (MCL).
Calquence is a Bruton tyrosine kinase (BTK) inhibitor. It works by blocking the activity of BTK, an enzyme involved in the growth and survival of cancer cells. By inhibiting BTK, Calquence helps to slow down or stop the growth of cancer cells.
The common side effects of Calquence include headache, diarrhea, fatigue, low red blood cell count (anemia), bruising, and muscle or joint pain.
Calquence is available in tablet form and is taken orally. The dosage and duration of treatment will depend on the individual's specific condition, as determined by their healthcare provider.
Yes, Calquence can be taken with or without food.
It is generally recommended to avoid consuming grapefruit and grapefruit juice while taking Calquence, as they may increase the levels of the medication in your blood.
Calquence may harm an unborn baby, so it is advised to avoid becoming pregnant while taking this medication. It is also recommended not to breastfeed while on Calquence, as it may pass into breast milk and harm the nursing baby.
The time it takes for Calquence to start working can vary from person to person, and also depends on the specific condition being treated. It is important to follow the prescribed dosage and treatment duration recommended by your healthcare provider.
If you have missed a dose of Calquence, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
The coverage for Calquence may vary depending on the insurance provider and the specific plan. It is recommended to check with your insurance company or pharmacist to understand the coverage and potential out-of-pocket expenses.
Calquence (acalabrutinib) is a medication used for the treatment of adults with certain types of blood cancers, including mantle cell lymphoma.
Calquence belongs to a class of drugs called Bruton's tyrosine kinase inhibitors. It works by blocking the activity of the abnormal proteins that promote the growth of cancer cells, thereby helping to slow down or stop the progression of the disease.
The common side effects of Calquence may include headache, diarrhea, tiredness, muscle and joint pain, upper respiratory tract infection, and rash. It is important to discuss any concerning side effects with your healthcare provider.
Calquence is taken orally in the form of capsules. The recommended dose and schedule may vary depending on the indication and individual patient factors. It is important to follow the instructions provided by your healthcare provider and not to modify the dosage without their guidance.
Yes, Calquence can be used alone or in combination with other treatments as prescribed by your doctor. The specific combination therapy will depend on your condition and medical history.
The exact timeframe for Calquence to work varies from person to person. Some patients may experience a reduction in their symptoms relatively quickly, while others may require a longer duration of treatment before seeing noticeable improvements. It is important to continue the medication as directed by your healthcare provider.
It is essential to inform your healthcare provider about your medical history, including any allergies, prior to starting Calquence. Certain medications or medical conditions may interfere with its efficacy or pose additional risks. Additionally, women who are pregnant or planning to become pregnant should discuss the potential risks and benefits with their doctor before starting treatment.