Beleodaq: Uses, Dosage, Demographic, Side Effects, Interactions, and Generic Options Beleodaq (belinostat) is a prescription medication that belongs to a class of drugs known as histone deacetylase inhibitors (HDAC inhibitors). It is used for the treatment of a certain type of cancer known as peripheral T-cell lymphoma (PTCL). Uses: Peripheral T-cell lymphoma (PTCL) is a rare type of non-Hodgkin's lymphoma that affects the T-cells. Beleodaq is used to treat PTCL in patients who have received at least one previous therapy and have relapsed or have become refractory to the previous treatment. It works by interfering with the DNA structure of the cancer cells and causing them to die. Dosage: Beleodaq is usually administered in a hospital or clinic setting, under the supervision of a healthcare professional. The recommended dose is 1,000 mg/m2 administered by intravenous infusion over 30 minutes on days 1-5 of a 21-day cycle. The dose may be adjusted based on the patient's individual response and tolerance. Demographic: Beleodaq is approved for use in adult patients with peripheral T-cell lymphoma who have failed or relapsed after previous treatment. It is not indicated for use in pediatric patients. Side Effects: Beleodaq may cause side effects in some patients. The most common side effects include: - Nausea - Vomiting - Fatigue - Anemia - Fever - Diarrhea - Decreased appetite - Constipation - Headache - Insomnia - Rash Other more serious side effects may include: - Decreased blood cell counts - Infections - Electrolyte imbalances - Severe cutaneous reactions - Respiratory distress syndrome - Tumor lysis syndrome Patients should contact their healthcare provider immediately if they experience any of these symptoms. Interactions: Beleodaq may interact with other medications, including: - CYP3A4 inhibitors and inducers - Warfarin - Antiplatelet agents - Anticoagulants Patients should inform their healthcare provider of any medications they are taking before starting treatment with Beleodaq. Generic Options: There are no generic options for Beleodaq at this time. In conclusion, Beleodaq is a histone deacetylase inhibitor that is used to treat peripheral T-cell lymphoma in adult patients who have failed previous therapy. It may cause side effects in some patients and may interact with other medications. Patients should contact their healthcare provider immediately if they experience any adverse reactions. There are currently no generic options available for Beleodaq.