Ampyra: A Comprehensive Guide for Patients Ampyra, also known by its generic name dalfampridine, is a medication used to improve walking in individuals with multiple sclerosis (MS). In this article, we will explore the uses, dosage, demographics, side effects, interactions, and generic options of Ampyra. Uses of Ampyra Ampyra is approved by the United States Food and Drug Administration (FDA) to improve walking in individuals with MS. The medication works by increasing the conduction of nerve signals in the body, which, in turn, helps to improve walking ability. Ampyra is not a cure for MS and does not treat any underlying disease. It only improves walking function. Dosage Ampyra comes in a 10mg tablet that is taken twice a day with a dose interval of 12 hours. The tablet should not be crushed, chewed, or broken, and should be taken with or without food. It is advised not to exceed the recommended dosage or frequency as this can lead to increased side effects of the medication. Demographics Ampyra is approved for individuals with MS who are experiencing walking difficulties. It is approved for use in individuals aged 18 years and older. The medication has not been studied in individuals with other types of neurologic conditions or in individuals with liver or kidney diseases. Therefore, caution should be exercised when prescribing the medication to this population. Side effects Ampyra can cause a range of side effects, some of which can be serious. Common side effects include: - Urinary tract infection - Insomnia - Dizziness - Headache - Nausea - Back pain Serious side effects include seizures, which are reported in individuals with a history of seizures, as well as allergic reactions. Interactions Ampyra can interact with other medications, such as drugs that impair kidney function, such as NSAIDs, and can increase the risk of kidney damage. Other medications that should be used with caution when taking Ampyra include drugs that lower the seizure threshold, such as tricyclic antidepressants and antipsychotics. Generic Options Dalfampridine is currently available as a generic medication and offers a more affordable option for patients. However, it is important to note that generic medications may differ slightly in formulation and can have different inactive ingredients. It is recommended to consult with a physician or pharmacist before switching to a generic form of any medication. Conclusion Ampyra is a medication used to improve walking function in individuals with MS. It is a valuable option for patients who experience mobility difficulties. However, it is essential to carefully monitor for side effects and drug interactions and adhere to the recommended dosage and frequency. With the availability of generic options, Ampyra is an affordable and accessible option for MS patients who need it.